Words similar to cytometric
Example sentences for: cytometric
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These data provide additional evidence that 4-AP exerts neither an anti-proliferative nor a pro-apoptotic influence on serum-supplemented GC cultures, because PCNA expression is a sensitive marker of GC proliferation and apoptosis [ 18 26 27 ] . The lack of 4-AP effect on GC viability is also evident from the flow cytometric analysis; the percentages of cells staining positive for propidium iodide were 8 ± 2% and 7 ± 2% in the presence and absence of drug (n = 4 samples of 10,000 cells/each from 4 GC isolations).
Subsequently, the flow cytometric data, based on the percentage of active cells, was supported by cytokine mRNA and ELISA data.
Tumor-associated variation in one or several pan-T cell antigens is a typical feature of neoplastic lymphocytes in many T-cell malignances and has been termed antigen "loss" or "deletion" [ 7 ] . Using immunohistochemistry on a large bank of T-cell lymphomas, we have previously noted a frequency of such antigen deletion of 18% for CD2, 26% for CD3, 30% for CD5 and 68% for CD7 [ 8 ] . Flow cytometric analysis can allow a more sensitive assessment of subtle variations in the levels of surface marker expression than immunohistochemistry [ 9 ] . In non-neoplastic T-cell populations, we noted relatively narrow range of CD3, CD4 and CD5 expression with majority of cells clustering within one log intensity.
Cluster analysis of abnormal flow cytometric immunophenotype is more reliable and easier to compare over time than morphologic analysis, and can detect PB involvement in a small number of cases without easily identifiable Sezary cells [ 12 ] . Routine flow cytometric profiling is also not as technically demanding as molecular monitoring [ 22 23 ] or electron microscopy.
In view of the flow cytometric data, we can infer that the enhanced mRNA in the CD8 +T cells derives primarily from the CD8 +CD28 -T cells.
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