Example sentences for: chemokine

How can you use “chemokine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The biological effects of chemokines are mediated by binding to G-protein-coupled, seven transmembrane domain, chemokine receptors [ 11 ] . CC receptors (CCR) bind members of the class of chemokines with two adjacent cysteine (C) residues near the NH 2 -terminus (CC; e.g.

  • Accordingly, correlation of cytokine and chemokine receptor expression might be important in delineating the function and potential means of accumulation of individual CD4 +memory T cells in the RA synovium.

  • Chemokine mRNA production by cell lines

  • Migration assays using supernatants of RA SCLs were employed to determine which of these chemokine and receptor interactions might be involved in monocyte migration in the RA synovium.

  • The involvement of Rho GTPases in regulating integrin dependent events such as leukocyte homotypic aggregation and in chemokine upregulation of integrin-mediated adhesion has recently been identified [ 18 19 ] . ADP-ribosylation of Rho in neutrophils by treatment with C3 not only inhibits cellular locomotion, but augments chemoattractant induced actin polymerization [ 20 21 ] . Moreover, inactivation of Rho in monocytic cells leads to accelerated formation of filopodia, and it has been proposed that Rho is a negative regulator of actin polymerization within this cell type [ 22 ] . Active Rho is also required for normal morphology, motility, and cytolytic activity of IL-2 activated NK cells [ 23 24 ] . We and others have demonstrated the importance of Rho in T lymphocyte activation [ 25 26 ] . Given the role played by Rho in the regulation of actin microfilaments in other cell types, and the indispensability of a functional actin cytoskeleton in lymphocyte motility and activation, it is of importance to study Rho's role in the regulation of T lymphocyte integrin function and maintenance of cytoskeletal organization.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast