Example sentences for: chemokine

How can you use “chemokine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some of the fibroblasts differentiate into myofibroblasts, which contract to close the wound [ 4 14 15 ] . Myofibroblasts are fibrogenic, showing elevated expression of interstitial collagens, laminin, FN and TN, and inhibitors of matrix metalloproteinases such as TIMP-1 [ 15 16 17 18 19 ] . Because cCAF is expressed highly in the granulation tissue of wounds in areas where ECM is abundant [ 3 6 11 ] , and it stimulates fibroblasts to differentiate into myofibroblasts [ 4 ] , we investigated whether this chemokine stimulates the production of the four major ECM molecules mentioned above, interstitial Colls I and III, TN and cellular FN.

  • The FN mRNA levels are not affected by cCAF treatment but the protein accumulates in culture and in the granulation tissue of wounds upon exposure to the chemokine.

  • This study demonstrates the expression of available chemokine binding sites for CCL2, CCL3, CCL5 and CXCL8 on CD68 +macrophages in the subintimal and intimal layers of rheumatoid and nonrheumatoid synovia.

  • Synovial samples that had been examined for chemokine binding were also sectioned and incubated with rabbit polyclonal antibodies to the carboxy termini of CXCR1 and CXCR2 (both from Santa Cruz Biotechnology, Santa Cruz, USA) [ 20 ] . Antibody binding was detected using an immunoperoxidase method (Vectastain ABC Elite Kit; Vector Labs, Burlingame, USA).

  • Immunolabeling of cells treated daily for four days with 750 ng/ml of the chemokine showed that cCAF stimulates the cells to produce more TN than the control cells (Fig.


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