Example sentences for: chemokine

How can you use “chemokine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the case of IP-10, it has been shown that in transgenic mice treated with this chemokine, wounds heal poorly and exhibit defects in angiogenesis and development of the granulation tissue [ 8 ] .

  • We also tested the effects of the chemokine on migration by using the cloning ring assay.

  • Interleukin-8 (IL-8) belongs to the CXC chemokine family and is secreted by several different cell types, including monocytes, neutrophils, endothelial cells, fibroblasts, and T lymphocytes.

  • We have previously determined, using dose-dependent studies, that this concentration is optimal for functions of this chemokine on these embryonic fibroblasts and in processes of granulation tissue formation [ 3 4 ] ). Although chemokine concentrations of 10 -2-10 ng/ml can chemoattract and activate leukocytes, chemokines acting on other cell types such as endothelial cells, smooth muscle cells and fibroblasts require concentrations in the range of 10 2ng/ml and higher [ 4 26 27 28 ] . This is within physiological range; for example wound fluid from burn patients contain MGSA (a chemokine that is highly homologous to cCAF) concentrations of 10 2-10 3ng/ml [ 29 ] . Because both the N-terminal and C-terminal peptides of cCAF have been shown to be functional in culture and in vivo (1-4, 30), we also tested these two peptides (Fig.

  • However, the role of chemokine receptor expression in the recruitment of T cells to these sites is unknown.


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