Words similar to chemopreventive
Example sentences for: chemopreventive
How can you use “chemopreventive” in a sentence? Here are some example sentences to help you improve your vocabulary:
Chemopreventive efficacy
Palpable mammary tumors were first detected after approximately 35 days following initation with NMU, and by 70 days incidence had reached 100% in rats not treated with chemopreventive agents (Fig.
Because locally elevated TGF-β levels could select for TGF-β-resistant cells, and because TGF-βs can have oncogenic effects on the stroma, it may actually be important for the safety profile of chemopreventive agents to demonstrate that they do not increase TGF-β levels in the at-risk breast.
While the evaluation of aspirin in the Min /+ model utilising a therapeutic regime is lacking, other NSAIDs (sulindac, flurbiprofen, piroxicam and celecoxib) have been shown to significantly reduce polyp numbers when administered using similar protocols [ 6 11 34 35 ] . In addition, three recent reports have demonstrated a lack of effect of aspirin as a chemopreventive agent in Min /+ mice [ 36 37 38 ] . Combined, these studies indicate that the Min /+ model is responsive to NSAIDs other than aspirin when provided as a treatment.
This suggests that there was minimal toxicity associated with the chemopreventive intervention, except in the tamoxifen + 4-HPR group, in which mild toxicity was observed.