Words similar to chemoprevention

Example sentences for: chemoprevention

How can you use “chemoprevention” in a sentence? Here are some example sentences to help you improve your vocabulary:

The American Cancer Society has indicated that cancer incidence rates are on the decline, however, they estimate that greater than 1.2 million new cases will be diagnosed this year [ 1 ] . Of these new cases, it is expected that colorectal cancers will comprise approximately 10-11% [ 1 ] . With staggering numbers as these, it is not surprising that chemoprevention has been proposed as a viable strategy to fight cancer.
In the present study we used a carcinogen-induced rat mammary carcinogenesis model to test the hypothesis that chemoprevention by tamoxifen and retinoids is associated with local upregulation of TGF-βs in the mammary gland, and that TGF-βs might therefore be useful as potential surrogate end-point biomarkers of chemopreventive efficacy in clinical trials.
Chemoprevention has been defined as the use of noncytotoxic nutrients or pharmacologic agents to enhance intrinsic physiologic mechanisms that protect the organism against the development of mutant clones and their progression to malignant cancer [ 27].
We have shown that treatment of rats with tamoxifen or retinoids results in effective chemoprevention of mammary tumorigenesis, without any detectable effect on local expression of TGF-βs.
Human clinical material for biomarker analysis in primary chemoprevention studies is also likely to comprise normal and initiated, at-risk epithelium with some early preneoplastic changes, but without evidence of major neoplastic change.