Words similar to chemoprevention
Example sentences for: chemoprevention
How can you use “chemoprevention” in a sentence? Here are some example sentences to help you improve your vocabulary:
In conclusion, we have shown that treatment of rats with tamoxifen or retinoids results in effective chemoprevention of mammary tumorigenesis, without any detectable effect on local expression of TGF-βs.
The NMU-induced rat model of mammary tumorigenesis is widely used for chemoprevention studies and yields rapid development of hormonally responsive mammary tumors with 100% incidence [ 2, 4, 18].
Although we cannot rule out more subtle effects on TGF-β activity, such as the activation of latent forms, the data suggest that the underlying molecular mechanism of chemoprevention by these agents does not involve increases in TGF-β expression.
In the present study we used a carcinogen-induced rat mammary carcinogenesis model to test the hypothesis that chemoprevention by tamoxifen and retinoids is associated with local upregulation of TGF-βs in the mammary gland, and that TGF-βs might therefore be useful as potential surrogate end-point biomarkers of chemopreventive efficacy in clinical trials.
The American Cancer Society has indicated that cancer incidence rates are on the decline, however, they estimate that greater than 1.2 million new cases will be diagnosed this year [ 1 ] . Of these new cases, it is expected that colorectal cancers will comprise approximately 10-11% [ 1 ] . With staggering numbers as these, it is not surprising that chemoprevention has been proposed as a viable strategy to fight cancer.