Example sentences for: chemotactic

How can you use “chemotactic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A plausible explanation is that these cytokines may be involved in complex interactions with other molecules that are chemotactic for DC.

  • Thus, by 12 hours post endotoxin administration, chemotactic responsiveness was at or below control levels.

  • MIG/CXCL9 and IP-10/CXCL10 are potent angiostatic factors that are induced by IFNγ [ 14 16 17 ] . Both MIG/CXCL9 and IP-10/CXCL10 are chemotactic for stimulated CXCR3-expressing activated T lymphocytes that could further amplify IFNγ at the tumor site [ 30 ] . Hence we postulated that in addition to IFNγ, IP-10/CXCL10 and MIG/CXCL9 would also be important contributors to the tumor reduction in the context of SLC/CCL21 therapy.

  • It has been shown that increasing amounts of Ang-2 can block the chemotactic activity of Ang-1 in endothelial cells [ 21 ] . Ang-2 alone did not stimulate corneal neovascularization, but the combination of Ang-2 and VEGF resulted in longer vessels with greater circumferential extent than those seen with VEGF alone [ 9 ] . This suggests that Ang-2 expression in the absence of VEGF leads to vessel regression, whereas expression of Ang-2 in the presence of VEGF potentiates angiogenesis.

  • For example, RP L18, which was significantly down-regulated by NGF, has been reported to negatively regulate double-stranded RNA (dsRNA)-activated protein kinase (PKR) [ 45 ] . As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] . As one last example, rat RP L9 which we found to be up-regulated by NGF starting within a few hours and maximally by 8 hrs, has been shown to be the ortholog of the yeast gene grc5 which appears to be involved in multiple cellular functions including growth control, cytoskeleton control and energy metabolism [ 47 ] . Identification of NGF-regulated RPs should now facilitate exploration of their potential roles in the responses of cells to neurotrophins.


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