Words similar to adenylyl
Example sentences for: adenylyl
How can you use “adenylyl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore, if combined with a drug such as fentanyl, or in the presence of an internal pool of β-endorphin, nalbuphine can act as an antagonist in inhibiting adenylyl cyclase by μ opioid receptors.
In order to understand the evolutionary affinities and provenance of the CyaB adenylyl cyclase from Aeromonas hydrophila , we carried out database searches using sensitive sequence profile analysis methods.
α s -GFP fusion proteins were assayed for the ability to stimulate adenylyl cyclase in response to luteinizing hormone (LH) receptor stimulation [ 38 ] . 10 6HEK 293 cells/60 mm-dish were co-transfected with 2 μg of plasmid DNA encoding the α s -GFP fusion protein, and 0.2 μg of plasmid DNA encoding the rat LH receptor in pCIS [ 39 ] , using 10 μL of Lipofectamine 2000.
We have shown that δ-opioids increase the phosphorylation of ERKl/2 in HEK-293 cells when the mouse wild type (WT) δ-OR is stably expressed [ 11 13 ] . The concentrations required to observe DSLET-mediated ERK phosphorylation (EC 50 = 10 nM; Figure 1a) are consistent with those reported for other δ-OR-mediated events, including G protein activation and adenylyl cyclase inhibition [ 16 17 ] . Moreover, no change in total ERK expression was observed, concomitantly, with ERK phosphorylation in any of our experiments (data not shown).
We also identify the potential active site- and substrate interacting-residues and postulate that these enzymes are likely to catalyze a two-metal ion dependent reaction on structural scaffold that is completely different from that seen in the other two superfamilies of adenylyl cyclases.
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