Example sentences for: adenylyl

How can you use “adenylyl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • mRNA for both Carl, the cell surface cAMP receptor, and AcaA, the adenylyl cyclase responsible for cAMP synthesis, was found to be induced 2 to 4 hours earlier than in the parental cells.

  • It has been reported that δ opioid receptors couple more efficiently to adenylyl cyclase system than to Ca 2+channels [ 7 ] . This evidence supports the use of cAMP system for assessing the activity of these receptors.

  • On the other hand, PGI 2 decreases vascular smooth muscle cell proliferation and collagen and glycosaminoglycane synthesis, via activation of adenylyl cyclase and subsequent production of cAMP [ 17 ] . Betaprost, an analog of PGI 2 , decreases procollagen I and III mRNA expression in cardiac fibroblasts [ 18 ] . These effects may counteract the profibrotic effects seen with TXA 2 and it is possible that an alteration of a "normal" physiologic balance between PGI 2 and TXA 2 could increase tendency towards fibrogenesis.

  • Whole cell adenylyl cyclase assays

  • We also identify the potential active site- and substrate interacting-residues and postulate that these enzymes are likely to catalyze a two-metal ion dependent reaction on structural scaffold that is completely different from that seen in the other two superfamilies of adenylyl cyclases.


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