Example sentences for: adenylation

How can you use “adenylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The crystal structure of the E. coli MoeB-MoaD complex clearly shows the interaction between these two proteins and unambiguously confirms the adenylation role of MoeB [ 7 ] . After a thiocarboxylate moiety is formed on the terminal glycine of each MoaD subunit, the two sulfur atoms are transferred to precursor Z as sulfhydryl groups in a dithiolene configuration.

  • We required that all matching ESTs or transcripts have clearly definable poly A tails and poly adenylation signals.

  • All 12 sequences in this region have high similarity to the derived consensus sequence GXGXXG(7X)A(SX)GXGXXG(4X)D(9X)R, which defines a nucleotide binding motif [ 16 25 ] . In addition, all sequences have five residues, or conservative substitutions in the case of Pa-MoeB, shown to participate in the adenylation reaction catalyzed by Ec-MoeB (Figure 3) [ 7 ] . The fact that such high similarities are retained in the ThiF coding region across three bacterial divisions suggests that this domain functions more or less autonomously.

  • The high degree of AA similarity that all 12 sequences have to the ThiF family domain probably indicates that these proteins, at least in part, perform a similar function, most likely activating a substrate by adenylation.

  • Positive identification required that the transcript or EST have a poly adenylation signal and poly A tail, and that the tag followed the most 3' CATG of the transcript.


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