Words similar to adenylation

Example sentences for: adenylation

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Positive identification required that the transcript or EST have a poly adenylation signal and poly A tail, and that the tag followed the most 3' CATG of the transcript.
All 12 sequences in this region have high similarity to the derived consensus sequence GXGXXG(7X)A(SX)GXGXXG(4X)D(9X)R, which defines a nucleotide binding motif [ 16 25 ] . In addition, all sequences have five residues, or conservative substitutions in the case of Pa-MoeB, shown to participate in the adenylation reaction catalyzed by Ec-MoeB (Figure 3) [ 7 ] . The fact that such high similarities are retained in the ThiF coding region across three bacterial divisions suggests that this domain functions more or less autonomously.
We required that all matching ESTs or transcripts have clearly definable poly A tails and poly adenylation signals.
The high degree of AA similarity that all 12 sequences have to the ThiF family domain probably indicates that these proteins, at least in part, perform a similar function, most likely activating a substrate by adenylation.
The crystal structure of the E. coli MoeB-MoaD complex clearly shows the interaction between these two proteins and unambiguously confirms the adenylation role of MoeB [ 7 ] . After a thiocarboxylate moiety is formed on the terminal glycine of each MoaD subunit, the two sulfur atoms are transferred to precursor Z as sulfhydryl groups in a dithiolene configuration.