Words similar to adenylylated

Example sentences for: adenylylated

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The second class, GSII, is found in all eukaryotes and a small number of prokaryotes, and appears to be involved in purine synthesis [ 35 ] . Unlike GSI, GSII is not adenylylated (and lacks the conserved tyrosine).
In the case of disruption of the Fhit and Hnt2-homologous aph1 gene in S. pombe , which encodes an enzyme relatively specific for a AppppA [ 20 ] , a 290-fold increase in AppppA concentration was observed [ 22 ] . Our data indicate that Hnt2 hydrolyzes ApppN and AppppN in vivo in budding yeast and that an intact adenine biosynthetic pathway is required for high-level synthesis and accumulation of adenylylated dinucleoside polyphosphates.
GSI, which to date appears restricted to prokaryotes [ 34 ] , is involved in ammonium assimilation as part of the nitrogen-fixation pathway in rhizobia [ 35 ] . The ability to be reversibly adenylylated at Tyr397 of the active site is a characteristic of GSI.
Consequently, it was suggested that a Kin28 monomer is the likely target of Hint regulation, potentially because it is post-translationally adenylylated and is a protein substrate of the lysine-deadenylylating activity of Hint [ 24].