Example sentences for: adenylate

How can you use “adenylate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although β-adrenoceptor desensitization [ 23] or reduced ATPase activity [ 25] may account for the decrease in basal heart rate in the hypertrophied male hearts, the increased sensitivity to isoproterenol may support the hypotheses of ischemia-induced activation of β-adrenoceptor kinase [ 26] or modulation of G-protein signaling to preserve adenylate cyclase activity [ 27].

  • cAMP is an important signaling molecule that can be found in specific cellular domains [ 53 ] . Levels are controlled through synthesis via adenylate cyclase, and degradation via phosphodiesterases (PDEs).

  • Earlier, Blackburn and co-workers made "supercharged" methane-trisphosphonic acid AppppA analogs containing a central carbon from which three adenylate or phosphate moieties are bonded [ 15 ] . In work presented here, tripodal inhibitors 15a and 17a showed, respectively, micromolar and submicromolar efficacies while the phosphorothioate counterparts 15b and 17b showed 100 nM efficacy.

  • 3shows that the signal, which regulates the expression of human CD8, is cAMP-mediated, since direct activation of adenylate cyclase by cholera toxin produced the same effects as the di-butiryl cAMP analog.

  • For many labile mRNAs, adenylate uridylate-rich elements (AREs) are required for their rapid degradation.


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