Words similar to adenylate

Example sentences for: adenylate

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In vitro experiments with rat GCs have demonstrated that BMP-4 and -7 inhibit and stimulate FSH-induced progesterone and estradiol production, respectively [ 4 ] . In related studies BMP-6 and BMP-15 were found to block FSH action through inhibiting FSH-dependent adenylate cyclase activity and FSH receptor expression, respectively [ 11 12 ] . The importance of these findings is underscored by the fact that FSH action is obligatory for normal folliculogenesis and female fertility.
For many labile mRNAs, adenylate uridylate-rich elements (AREs) are required for their rapid degradation.
Earlier, Blackburn and co-workers made "supercharged" methane-trisphosphonic acid AppppA analogs containing a central carbon from which three adenylate or phosphate moieties are bonded [ 15 ] . In work presented here, tripodal inhibitors 15a and 17a showed, respectively, micromolar and submicromolar efficacies while the phosphorothioate counterparts 15b and 17b showed 100 nM efficacy.
These inhibitory actions of 4-AP on adenylate cyclase activity, StAR expression and steroidogenesis may reflect drug-induced changes in the intracellular concentrations of K +and Cl -and the GC resting membrane potential.
cAMP is an important signaling molecule that can be found in specific cellular domains [ 53 ] . Levels are controlled through synthesis via adenylate cyclase, and degradation via phosphodiesterases (PDEs).