Example sentences for: accumulation

How can you use “accumulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These studies indicate that PP5 participates in the regulation of GR nucleocytoplasmic shuttling, and that the suppression of PP5 expression results in the nuclear accumulation of GR in the absence of hormone.

  • The accumulation of non-secreted protein in mutants defective in ER to Golgi transport leads to proliferation of the ER [ 37 44 ] . The membrane proliferation seen by TEM in npa1-1/sec23 and npa2-1/sec13 cells (Figure 4) and the coincident mislocalization of Nups (Figure 3and data not shown) prompted us to test if Nups were accumulating at the ER.

  • This approach is not readily applicable to the Wnt response because the critical step in signal transduction is the block in β-catenin phosphorylation and degradation, leading to the accumulation of newly-synthesized β-catenin.

  • The only phenotype known to be shared by srp1, mtr10, and kap104 mutants is accumulation of the 60S ribosomal protein Rpl11b in the nucleus [ 39 ] . SRP1, MTR10, and KAP104 may also collaborate to maintain the proper nucleocytoplasmic partitioning of α factor (or factors) that regulates mitotic exit.

  • Sixteen searchers, a search dog and a helicopter were being used to search today, but rain and six to 10 inches of new snot, with a total accumulation of two to three feet at those elevations, are hampering operations.


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