Example sentences for: accumulates

How can you use “accumulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, some mutant SOD1 causes motor neuron degeneration without mitochondrial vacuolation [ 8 11 36 ] . One difference between the mutants that induce vacuoles and the ones that do not, is that the former accumulates at higher levels in the mouse spinal cord than that latter.

  • The non-fluorescent BSA conjugate is internalized into cells through the endocytic pathway, and accumulates in lysosomes where the extent of its oxidation depends on the oxidative activity in this organelle.

  • The first is based on observations that PLD2 is inhibited by α-synuclein [ 36 ] , a protein of unknown function that accumulates in the amyloid deposits in AD brain.

  • While expression of wild-type human protein does not significantly alter overall β-catenin levels, stabilized protein accumulates in hippocampal, cortical and cerebellar neurons and translocates into their nuclei.

  • Its principal metabolite, normeperidine, has no analgesic properties of its own, has a longer half-life of about 6 hours, is renally excreted, and produces significant adverse effects when it accumulates.


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