Words similar to ubiquitin-conjugating
Example sentences for: ubiquitin-conjugating
How can you use “ubiquitin-conjugating” in a sentence? Here are some example sentences to help you improve your vocabulary:
UBC: ubiquitin-conjugating enzyme
As Pcu3p-associated ubiquitin ligase activity was not described before, we first needed to determine which of the fourteen different ubiquitin-conjugating enzymes (UBCs) present in the fission yeast genome associate with the RING domain protein Pip1p, an essential cofactor of cullin ubiquitin ligases [ 7, 28, 29, 30].
SCF complexes share homologues of the core components cullin 1 (CUL1), SKP1, and the RING domain protein HRT1/RBX1/ROC1, which associate with different F-box proteins and ubiquitin-conjugating enzymes [ 1].
The addition of a polyubiquitin chain to a protein requires the sequential action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2) and a ubiquitin-protein ligase (E3) [ 1 ] . E3 activities are thought to be essential because they are involved in substrate recognition.
For example, the ubiquitin-conjugating enzyme, which is important in protein degradation, identifies 6 unknown proteins out of 12, with 'C' or above confidence, which contain similar domains.