Example sentences for: ubiquitin

How can you use “ubiquitin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In fact, p27 depletion in several cancers was shown to result from increased proteolysis via the ubiquitin/proteasome system [ 15 16 17 18 ] .

  • To determine whether ubiquitin was conjugated directly to Rab24(D123I), it was necessary to solubilize the protein aggregates in a high-detergent buffer that was incompatible with standard immunoprecipitation methods.

  • An immunofluorescence study was performed to determine whether or not the intranuclear Rab24(D123I) aggregates might sequester ubiquitin and Hsp70.

  • In principle, deubiquitination could be used for (1) recycling of ubiquitin, (2) abetting degradation by removal of the tightly folded highly stable globular ubiquitin domain, or (3) mitigating degradation by removal of the ubiquitin anchor, without which the substrate is easily released and rescued.

  • The increased expression of βTrCP/slimb [ 26 ] and the ubiquitin conjugating enzyme Ubc4/5E2 (Figure 1), both involved in degradation of β-catenin [ 27 ] , could act as a negative feedback loop in Wnt signaling.


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