Example sentences for: ubiquitin

How can you use “ubiquitin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A number of RING finger proteins have recently been shown to act as E3 ubiquitin ligases [ 24 ] . WD40 domains have also been frequently found in E3 complexes as substrate recruiting domains [ 25 26 27 28 ] . Despite compelling evidence from Arabidopsis implying that COP1 may mediate protein degradation [ 4 5 ] , no direct evidence of COP1 participating in ubiquitination has been reported.

  • These enzyme complexes each recognize a subset of substrates and tag them by linking the carboxyl terminus of ubiquitin with an amino group on the target protein via an amide bond (Figure 1).

  • Upon an auxin stimulus, an SCF (SKP1/Cullin/F-box protein) ubiquitin ligase (Deshaies 1999) containing the TIR1 F-box protein ubiquitinates the Aux/IAA proteins, marking them for degradation by the 26S proteasome thereby de-repressing the response pathway (Gray et al.

  • In addition, we required an ubiquitin activating enzyme (E1) and an ubiquitin conjugating enzyme (UBC).

  • The inclusions bear a superficial resemblance to those described in some of the polyglutamine disorders, and appear to sequester Hsp70, ubiquitin, importin-β, and glucocorticoid receptor.


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