Words similar to ubiquitylation

Example sentences for: ubiquitylation

How can you use “ubiquitylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

In contrast, the ubiquitylation assay with Pcu3p-Myc complexes purified from csn5 mutants led to efficient formation of high molecular weight species reactive with ubiquitin antibodies (Fig.
Substrate-independent in vitro ubiquitylation activity was determined by immunoprecipitating Pop1p-13Myc or Pop2p-13Myc with Myc antibodies.
The protein product of the mdm2 oncogene is over-expressed in a considerable number of tumors [ 27 ] . This protein is a pivotal negative regulator of p53 [ 27 ] ; it interacts with the P53 protein masking its transcriptional domain and accelerating its proteasomal degradation [ 21 27 ] . The later process involves the deacetylation and ubiquitylation of the p53 protein by mdm2 [ 28 ] . Inactivation and/or degradation of p53 diminishes the cell ability to undergo apoptosis [ 21 ] . Conversely, p53 may influence mdm2.
3C), suggesting that p27 accumulation results from reduced p27 ubiquitylation.
Importantly, SKP2 overexpression is sufficient to reverse androgen-mediated p27 accumulation and induce p27 ubiquitylation (Fig.