Example sentences for: ubiquitination

How can you use “ubiquitination” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Post-transcriptional controls appear to be the major regulatory mechanisms that determine the levels of p27 Kip1in the cell [ 26 ] . These include ubiquitination and proteasomal degradation [ 27 ] and sequestration and mislocalization [ 28 ] of the p27 Kip1protein.

  • Our results suggest that mammalian COP1 might play a role in ubiquitination (Fig 2).

  • To further investigate whether COP1 itself undergoes ubiquitination, a His-tagged ubiquitin expression construct (His-Ub) was co-transfected into the 293 cells with FLAG-COP1, followed by His purification under denaturing condition (in 8 M Urea).

  • Evidence for a role of COP1 in protein ubiquitination in vivo

  • This RING-fmger domain has been shown to be necessary for the ubiquitination function of Siah1a [ 46 ] . As a positive control for expression, this construct was fused to the C-terminus of GFP (figure 5A).


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