Words similar to ubiquitinated

Example sentences for: ubiquitinated

How can you use “ubiquitinated” in a sentence? Here are some example sentences to help you improve your vocabulary:

In addition, Skp2 knock-out cells do not accumulate E2F [ 21 ] and an E2F mutant unable to bind Skp2 is still ubiquitinated and unstable [ 21 ] . Thus, the basis of S phase destruction of E2F-1 remains unresolved.
Moreover, immunoblot analysis of the His 6 Rab24(D123I) isolated from cells treated with lactacystin (to block degradation of poly-ubiquitinated proteins by the 26S proteasome) showed no detectable ubiquitin associated with the protein, although the same antibody detected multiple ubiquitinated polypeptides in the whole-cell lysate (Fig.
The best-characterized example of ubiquitin-independent degradation is the degradation of ornithine decarboxylase (ODC), which is dependent upon ODC interaction with the targeting protein antizyme (Az) [ 18 ] . How ubiquitinated substrates or Az-bound ODC is recognized by the 26S proteasome is not well understood.
In this study, we have demonstrated the mammalian COP1 is associated with ubiquitinated proteins and itself a substrate for ubiquitination in vivo.
Again, these findings agree with recent studies of poly-Gln protein aggregates, which indicate that although ubiquitinated proteins are present in the inclusions, they are not conjugated directly to the initiating poly-Gln polypeptide [ 60 ] .