Words similar to ubiquitinated
Example sentences for: ubiquitinated
How can you use “ubiquitinated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Under these conditions the receptor is ubiquitinated and degraded.
Immunoblot analysis of the immunoprecipitates with anti-HA antibodies detected multiple distinct bands and smear only when FLAG-COP1 and HA-Ub were co-expressed, indicating that at least a subset of COP1 associated proteins are ubiquitinated in human cells (Fig.
Moreover, we show that mammalian COP1 is associated with ubiquitinated proteins in vivo and itself a substrate of ubiquitination.
Moreover, immunoblot analysis of the His 6 Rab24(D123I) isolated from cells treated with lactacystin (to block degradation of poly-ubiquitinated proteins by the 26S proteasome) showed no detectable ubiquitin associated with the protein, although the same antibody detected multiple ubiquitinated polypeptides in the whole-cell lysate (Fig.
Therefore, mammalian COP1 not only associates with ubiquitinated proteins in vivo, but also itself a substrate for multi-ubiquitination.