Words similar to ubiquitin-dependent

Example sentences for: ubiquitin-dependent

How can you use “ubiquitin-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

In unstimulated cells, the mdm2 protein binds to the N-terminal transactivation domain of p53 and targets it for ubiquitin-dependent degradation [ 6, 7].
The well-known ubiquitin-dependent pathway involves the covalent attachment of ubiquitin to substrate proteins to form polyubiquitin chain, which then targets the marked substrates to proteasome for degradation [ 17 19 20 ] . The ubiquitin-independent pathway is not well defined, but involves targeting proteins other than ubiquitin.
The 20S proteasome then combines with two 19S regulatory complex to form the 26S proteasome, which is the degradation machinery responsible for both ubiquitin-dependent and ubiquitin-independent degradation [ 37 ] . The prosequences of the proteolytic β subunits are important to keep the proteolytic sites inaccessible to the substrates.
In A. thaliana , CSN was shown to be required for the efficient nuclear accumulation of the putative RING-type ubiquitin ligase COP1 [ 24], which mediates ubiquitin-dependent degradation of the photomorphogenic transcription factor HY5 [ 25].