Words similar to ubiquitin-dependent

Example sentences for: ubiquitin-dependent

How can you use “ubiquitin-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

The 20S proteasome then combines with two 19S regulatory complex to form the 26S proteasome, which is the degradation machinery responsible for both ubiquitin-dependent and ubiquitin-independent degradation [ 37 ] . The prosequences of the proteolytic β subunits are important to keep the proteolytic sites inaccessible to the substrates.
In unstimulated cells, the mdm2 protein binds to the N-terminal transactivation domain of p53 and targets it for ubiquitin-dependent degradation [ 6, 7].
In A. thaliana , CSN was shown to be required for the efficient nuclear accumulation of the putative RING-type ubiquitin ligase COP1 [ 24], which mediates ubiquitin-dependent degradation of the photomorphogenic transcription factor HY5 [ 25].
The well-known ubiquitin-dependent pathway involves the covalent attachment of ubiquitin to substrate proteins to form polyubiquitin chain, which then targets the marked substrates to proteasome for degradation [ 17 19 20 ] . The ubiquitin-independent pathway is not well defined, but involves targeting proteins other than ubiquitin.