Example sentences for: ubiquitin-mediated

How can you use “ubiquitin-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This latter domain is commonly associated with several proteasomal and signalosomal proteins and is involved in ubiquitin-mediated protein degradation [ 50].

  • Further analysis of the CSN will no doubt uncover additional mechanisms whereby ubiquitin-mediated protein degradation is controlled.

  • MG-132 is a peptide aldehyde that inhibits ubiquitin-mediated proteolysis by binding to and inactivating 20S and 26S proteasomes [ 49 62 ] . Although 1-10 μM MG-132 inhibited first polar body extrusion in rat oocytes, its activity is reversible [ 42 ] . We conducted preliminary experiments to obtain a MG-132 dose range that would transiently perturb or inhibit OM during meiosis I while enabling oocytes to complete OM following washing out of the compound.

  • The ubiquitin-mediated degradation of key regulatory proteins has been demonstrated, or is at least likely, for all of the phytohormone response pathways (Smalle and Vierstra 2004).


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