Words similar to ubiquitin-independent

Example sentences for: ubiquitin-independent

How can you use “ubiquitin-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:

The 20S proteasome then combines with two 19S regulatory complex to form the 26S proteasome, which is the degradation machinery responsible for both ubiquitin-dependent and ubiquitin-independent degradation [ 37 ] . The prosequences of the proteolytic β subunits are important to keep the proteolytic sites inaccessible to the substrates.
This could be a common mechanism for ubiquitin-independent degradation pathways.
The best-characterized example of ubiquitin-independent degradation is the degradation of ornithine decarboxylase (ODC), which is dependent upon ODC interaction with the targeting protein antizyme (Az) [ 18 ] . How ubiquitinated substrates or Az-bound ODC is recognized by the 26S proteasome is not well understood.
The well-known ubiquitin-dependent pathway involves the covalent attachment of ubiquitin to substrate proteins to form polyubiquitin chain, which then targets the marked substrates to proteasome for degradation [ 17 19 20 ] . The ubiquitin-independent pathway is not well defined, but involves targeting proteins other than ubiquitin.