Example sentences for: smad

How can you use “smad” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, this alternate pathway may explain the TGFβ 1 resistance of cells with no detectable defect in the SMAD pathway [ 92 93 94 95 96 97 98 99 100 101 ] , as one can imagine that the cooperative action of the both pathways is necessary to exert the complete growth inhibitory effect of TGFβ 1 . Comparable effects have been described for the synergistic operation of growth factor receptor and anchorage dependent integrin signaling [ 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 ] .

  • We found that preincubation of cells with either SB-202190 or SB-203580 decreased the level of nuclear Smad3 in the presence of TGFβ (Fig.

  • Among the thirteen isolated Smad1 interactors, only clones 13, 17, 19 and 21 bind Smad2, whereas only clones 1, 17 and 21 exhibit strong interaction with Smad3.

  • We were intrigued by the fact that Smad1 binds to Ub, Az and HsN3, all of which are involved in proteasome-mediated degradation pathways, as illustrated in Fig.

  • The genes being examined were divided into two groups: I, known TGFβ target genes: pai-1, smad7, c-myc, upa and pthrp (Fig.


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