Words similar to sma-negative
Example sentences for: sma-negative
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Our assumption is in agreement with our previous findings, which have revealed that focal disruptions of ME cell layers could lead to a significantly higher proliferation rate in subjacent epithelial cells [ 12 33 ] . Our assumption is also supported by a recent study showing that normal and tumor-derived ME cells differ substantially in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition [ 37 ] . Further studies are currently in progress to elucidate the biological behavior and genetic profile of epithelial cells immediately subjacent to these SMA-negative ME cells.
In double immunostained sections, these SMA-negative cells were also devoid of distinct immunostaining for any of the additional eight markers (Fig.
The SMA-negative cells in all three cases showed distinct negativity to ER and CK8, in sharp contrast with the overlying epithelial cells that showed strong ER and CK8 positivities (data not shown).
In addition, sections from all three cases were immunostained for estrogen receptor (ER) and CK8 to exclude the possibility that these SMA-negative cells might be epithelial in nature.
The distribution of these SMA-negative ME cells seemed to be independent of the ductal size, length, and architecture.