Example sentences for: smad-independent

How can you use “smad-independent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • After binding to α V β 6 integrin, latent TGFβ 1 is activated by processing of latent TGFβ 1 by cleavage of the latency-associated Peptide (LAP) [ 45 46 47 48 49 50 51 52 53 54 55 56 57 ] . Recently, the interaction of latent TGFβ 1 with α V β 6 integrin has been shown [ 45 ] . After binding of latent TGFβ 1 to α V β 6 integrin, latent TGFβ 1 is activated by cleavage of the latency-associated peptide (LAP) [ 45 ] . This α V β 6 integrin is also expressed by pancreatic carcinoma cells [ 58 59 60 61 62 63 ] . We hypothesized that there is a SMAD-independent TGFβ 1 signaling pathway in TGFβ 1 -sensitive carcinoma cells.


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