Example sentences for: smads

How can you use “smads” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The requirement of both Smad1 and Smad4 in the down-regulation of SNIP1 is interesting since this may represent an important molecular mechanism for the co-operative property of these Smads to modulate transcription.

  • However, our current knowledge of the molecular events involved in the recruitment of CBP/p300 and other transcriptional co-activators or co-repressors by Smads is still very limited.

  • Three such BMP type I receptor-regulated Smads, Smad1, 5 and 8, have been identified [ 9 ] . Among them, Smad1 has been studied most extensively.

  • Although there are multiple reports on proteasomal degradation of Smads and Smad interacting proteins, primarily in TGF-β signaling pathways [ 47 48 49 50 51 52 53 54 ] , our observations reported here are entirely based upon our own original observations and show a novel connection of Smads with the proteasome system that no other groups have reported.

  • Smads have been shown to mediate transcription via modulating the transcriptional activity of many other DNA-binding proteins.


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