Words similar to smads

Example sentences for: smads

How can you use “smads” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, we propose that such degradation is coupled to the recruitment of the SNIP1-free CBP/p300 to a nearby DNA-binding transcription factor, thus carrying out the commonly observed role of Smads as transcriptional co-modulators.
Smads have been shown to mediate transcription via modulating the transcriptional activity of many other DNA-binding proteins.
Considering the sophisticated mode of regulation characteristic of the TGF-β/BMP family ligands, it is expected that that signaling mechanisms of Smads should have a nature of complexity that can accommodate the vast biological functions of these regulators.
However, our current knowledge of the molecular events involved in the recruitment of CBP/p300 and other transcriptional co-activators or co-repressors by Smads is still very limited.
TGFβ signals through a heteromeric receptor complex of type II and type I receptor serine-threonine kinases, which activates the downstream Smad signal transduction pathway [ 7 ] . After TGFβ binding to the receptor complex, the TGFβ type II receptor kinase phosphorylates TGFβ type I receptor which inititates the downstream response by phosphorylating receptor-regulated Smads (R-Smads), such as Smad2 and Smad3.