Words similar to smads

Example sentences for: smads

How can you use “smads” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, our current knowledge of the molecular events involved in the recruitment of CBP/p300 and other transcriptional co-activators or co-repressors by Smads is still very limited.
The chaperon proteins such as Hsc73 could be involved in unfolding the substrates for them to fit into the degradation chamber and the final maturation of 20S proteasome from the 16S assembly intermediates could trap the substrates, such as Ump1 and Smads, inside the degradation chamber.
The ability of Smad1 and Smad4 to target SNIP1 for degradation, thereby freeing CBP/p300 for other transcriptional factors is likely an important mechanism for the transcriptional modulator role of these two Smads.
Considering the sophisticated mode of regulation characteristic of the TGF-β/BMP family ligands, it is expected that that signaling mechanisms of Smads should have a nature of complexity that can accommodate the vast biological functions of these regulators.
TGFβ signals through a heteromeric receptor complex of type II and type I receptor serine-threonine kinases, which activates the downstream Smad signal transduction pathway [ 7 ] . After TGFβ binding to the receptor complex, the TGFβ type II receptor kinase phosphorylates TGFβ type I receptor which inititates the downstream response by phosphorylating receptor-regulated Smads (R-Smads), such as Smad2 and Smad3.