Example sentences for: small-molecule

How can you use “small-molecule” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This supports the model that all of these small-molecule modulators of Hh signaling are direct ligands of Smo.

  • Folds such as the SH3-like barrels, the PAS-like fold, the OB fold, the double-stranded β-helix, the β-propeller and rubredoxin-like zinc ribbons are predominantly non-catalytic domains that are widely represented in multiple functional contexts, with roles such as small-molecule binding, nucleic-acid binding and interaction with other proteins [ 3, 4, 5] (see also the SCOP [ 6] and CATH [ 7] databases).

  • This proliferation of the small-molecule dioxygenases is consistent with their possible role in the synthesis of secondary metabolites in these organisms [ 1, 6, 7, 30].

  • It is clear that, to the extent that small-molecule kinase inhibitors are effective as single agents in treatment of cancer, resistance will develop.

  • Both of these mutations are associated with sensitivity to the small-molecule kinase inhibitors gefitinib or erlotinib [1,2,3].


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