Words similar to small-molecule
Example sentences for: small-molecule
How can you use “small-molecule” in a sentence? Here are some example sentences to help you improve your vocabulary:
The original report on the crystal structure of the photosynthetic reaction center suggested that the region corresponding to the PRC-barrel of the PRC-H subunit could bind a small-molecule ligand [ 14].
Folds such as the SH3-like barrels, the PAS-like fold, the OB fold, the double-stranded β-helix, the β-propeller and rubredoxin-like zinc ribbons are predominantly non-catalytic domains that are widely represented in multiple functional contexts, with roles such as small-molecule binding, nucleic-acid binding and interaction with other proteins [ 3, 4, 5] (see also the SCOP [ 6] and CATH [ 7] databases).
These observations suggest that the Ptc-Smo receptor circuit may incorporate native small-molecule ligands in the regulation of Hh signaling.
Furthermore, studies with the agonist and several antagonists of Hh signaling suggest that Smo can be activated or inhibited by direct interaction with small-molecule ligands.
To identify small-molecule agonists of Hh signaling, we established a mammalian-cell-based assay.
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