Words similar to small-molecule

Example sentences for: small-molecule

How can you use “small-molecule” in a sentence? Here are some example sentences to help you improve your vocabulary:

Small-molecule modulators of growth-factor pathways have proven valuable in providing enhanced understanding of the intracellular events that occur subsequent to receptor activation, and in establishing the biological functions of these pathways [ 6 7 8 ] . In Hh signaling, multiple insights have been gained through the use of the plant-derived Hh antagonist cyclopamine [ 9 10 11 12 13 14 15 16 ] and a recently identified synthetic small-molecule Hh-signaling inhibitor, Cur61414 [ 17 ] . Interestingly, these specific inhibitors of Hh signaling appear to function downstream of Ptc but their precise molecular target(s) and mechanism of action are unknown.
One involved identification of a non-peptide activator of the granulocyte colony-stimulating factor (GCSF) pathway that appeared to act via receptor oligomerization [ 18 ] . Another report described a small-molecule activator of the insulin-signaling pathway that also acts at the level of the receptor [ 19 ] .
As might have been anticipated in treatment of cancer with any single agent, resistance to small-molecule tyrosine kinase inhibitors has emerged as a significant clinical problem.
They were probably derived from small-molecule hydroxylases early in eukaryotic evolution.
To identify small-molecule agonists of Hh signaling, we established a mammalian-cell-based assay.