Words similar to smad-
Example sentences for: smad-
How can you use “smad-” in a sentence? Here are some example sentences to help you improve your vocabulary:
Data from western blot analyses using Ab specific for phosphorylated epitopes of Smad-1 as well as analyses of dendritic growth in cultures exposed to BMP-5 in the presence of a soluble BMPR-IA-Fc chimeric protein are consistent with a signaling pathway that involves binding to the BMPR-IA and activation of Smad-1.
5 μg/ml for BMP-5 Ab; 10 μg/ml for Smad-1 Ab).
It has been shown that phosphorylation of Smad-1 precedes dendritic extension in cultured sympathetic neurons exposed to BMP-7; moreover, expression of a dominant negative construct of Smad-1 in cultured sympathetic neurons significantly inhibits BMP-7-induced dendritic growth in these neurons [ 23 ] . These data suggest that activation of Smad-1 is a necessary component of the signal transduction pathway by which BMP-7 induces dendritic growth.
Ab specific for the phosphorylated form of Smad-1 (Ser 463/465) as well as Ab that recognizes both phosphorylated and nonphosphorylated Smad-1 (e.g.
In most cell systems that have been examined, the primary signal transduction pathway for BMPs involves phosphorylation of Smad-1 [ 22 ] , and recent evidence suggests that this is also true for BMP-7 induced dendritic growth in sympathetic neurons [ 23 ] . To determine if BMP-5 initiates similar signaling events in sympathetic neurons, cultured sympathetic neurons grown in the absence of glial cells were treated with BMP-5 for 30 or 60 min then analyzed by Western blotting using Abs specific for total Smad-1 or for phosphorylated Smad-1.
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