Words similar to pka
Example sentences for: pka
How can you use “pka” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the other hand, it has been previously demonstrated that direct activation of adenylate cyclase by Forskolin or cholera toxin, inhibition of cAMP-specific phosphodiesterase, and treatment with a cell permeable cAMP analog, induces a rise in intracellular cAMP [ 22 23 24 25 26 ] . Since cAMP is known to modulate the expression of CD8 in mice [ 27 ] , we sought to determine whether cAMP-dependent protein kinase (PKA)-mediated signaling plays a role in modulating the mRNA levels of CD3, CD4, and CD8 in ex vivo examined human thymocytes.
C; catalytic subunit, cAMP; cyclic adenosine monophosphate, CAT; chloramphenicol acetyl transferase, C/EBP; CAAT/enhancer binding protein, ChoRE; carbohydrate response element, CMV; cytalomega virus, 8-CPT-cAMP; 8-(4-chlorophenyl)thio-cAMP, CREB; cAMP-response element binding protein, EMSA; electrophoretic mobility shift assay, FAS; fatty acid synthase, FSH; follicle stimulating hormone, GIRE; glucose/insulin response element, hCG; human chorionic gonadotrophin, HLH; helix-loop-helix, IRE; insulin response element, MHC; major histocompability complex, PGHS; prostaglandin G/H synthase, PKA; cAMP-dependent protein kinase, R; regulatory subunit, USF; upstream stimulating factor, WB; Western blot.
Experiments using various protease inhibitors indicated that the changes in complex mobility were due to inhibitory effects of PKA on the protease calpain.
Differential compartmentation of these signaling molecules in cells and tissues is being recognized as a mechanism to regulate their specificity [reviewed recently by [ 6 ] ]. A Kinase Anchoring Proteins (AKAPs) can direct their subcellular localization by binding directly to regulatory subunits of PKA or to the catalytic core of PKC.
Approximately 20% of the ORs do not have any serine or threonine residues in their carboxyl termini, whereas the remaining 80% have an average of more than two such residues, most of which are located in the vicinity of positively charged amino acids and conform to consensus sequences for phosphorylation by PKC or PKA.
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