Words similar to pka
Example sentences for: pka
How can you use “pka” in a sentence? Here are some example sentences to help you improve your vocabulary:
RIIα - PKA regulatory type II subunit alpha
C; catalytic subunit, cAMP; cyclic adenosine monophosphate, CAT; chloramphenicol acetyl transferase, C/EBP; CAAT/enhancer binding protein, ChoRE; carbohydrate response element, CMV; cytalomega virus, 8-CPT-cAMP; 8-(4-chlorophenyl)thio-cAMP, CREB; cAMP-response element binding protein, EMSA; electrophoretic mobility shift assay, FAS; fatty acid synthase, FSH; follicle stimulating hormone, GIRE; glucose/insulin response element, hCG; human chorionic gonadotrophin, HLH; helix-loop-helix, IRE; insulin response element, MHC; major histocompability complex, PGHS; prostaglandin G/H synthase, PKA; cAMP-dependent protein kinase, R; regulatory subunit, USF; upstream stimulating factor, WB; Western blot.
IBMX: isobutylemthylxnthine/PMA: 12-tetradecanoylphorboMS acetate/PKA: cAMP-dependent Protein Kinase/PKC: Protein Kinase C
The diffusion of these soluble second messengers leads to the activation of PKA and PKC at specific subcellular locations [ 3 4 ] . The two families of the regulatory subunits of PKA, RI and RII, have distinct cAMP binding properties and phosphorylation states [ 4 5 ] . Each family has two different isoforms, a and (3, resulting in four distinct types, RIα, RIβ, RIIα, RIIβ.
On the other hand, cAMP is known to participate in the growth and differentiation of varied cell types (including thymocytes), through the transcriptional regulation of specific genes [ 32 33 34 ] . The unique cAMP signaling which specifically targets the expression of the CD8 mRNAs (α and β), suggests that PKA activation may result in the transduction of signals that determine the selection of T lymphocytes in favor of the CD4 +CD8 -lineage, by down-regulating and possibly turning off the expression of the CD8 transcripts.
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