Words similar to pkc
Example sentences for: pkc
How can you use “pkc” in a sentence? Here are some example sentences to help you improve your vocabulary:
Both have been shown to elevate intracellular Ca 2+levels and to activate PKC and CamKII [ 4 5 6 ] . In addition Wnt-5a and Rfz-2 have been shown to synergize in their induction of CamKII [ 6 ] . Wnt-1/C57mg cells were also used for comparison, in an effort to identify genes preferentially regulated by Wnt-5a.
Recently, we reported that phorbol ester inhibited Ca 2+influx through PKC-dependent and PKC-independent pathways [ 21 ] . In the present study, we further evaluated the non-PKC mechanism of PMA action on β-cell electrical excitation by using patch-clamp techniques.
HSP20 has a second phosphorylation site, presumptively phosphorylated by PKC [ 12 ] , of unclear significance.
In the NetSearch-generated model, Bck1p is downstream of Mkk1p because, although it interacts with both Mkk1p and Mkk2p, it has been shown specifically not to interact with Pkc1p in two-hybrid assays [ 18 ] .
Neurogranin has been shown to be phosphorylated by PKCγ, and this phosphorylation is greatly decreased in PKCγ knockout mice, suggesting neurogranin is a PKCγ-specific substrate [ 9 ] . Evidence that strongly suggests the phosphorylation of neurogranin plays an important role in neural plasticity comes from the studies that demonstrated neurogranin knockout mice show essentially the same deficits in behaviors related to learning and memory as that of the PKCγ knockout mice [ 10 ] . Neurogranin is not only a substrate of PKCγ, but also plays a important role in regulating PKC signaling [ 11 ] . Interstingly, PKCγ knockout mice demonstrate reduced neuropathic pain [ 12 ] . Similar to neurogranin, we found that a calmodulin-binding, vesicle-associated, CAM kinase IV-like protein is highly expressed and enriched in the superficial layer of the dorsal spinal cord.
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