Words similar to pkc

Example sentences for: pkc

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Both have been shown to elevate intracellular Ca 2+levels and to activate PKC and CamKII [ 4 5 6 ] . In addition Wnt-5a and Rfz-2 have been shown to synergize in their induction of CamKII [ 6 ] . Wnt-1/C57mg cells were also used for comparison, in an effort to identify genes preferentially regulated by Wnt-5a.
Pretreatment of cells with the PKC inhibitor, BIM (1 μM) for about 60 min did not prevent PMA-induced hyperpolarization (Fig.
The blots show that PKCα, the major PKC isoform present in muscle, is not detected by the PKCβII antibody, and that there is little overlap between the specificities of the PKA regulatory subunit antibodies.
Selected AKAPs have been identified that can interact with both PKA and PKC [ 12 13 ] . For example, it was shown that AKAP 79 maintains PKA, PKC, and protein phosphatase 2B at the postsynaptic density of mammalian synapses [ 14 12 ] . Likewise, gravin, a second PKA/PKC anchoring protein, targets these kinases to the membrane cytoskeleton [ 13 ] . AKAP79, gravin, and its mouse homolog clone 72 thus belong to the recently identified class of scaffolding proteins that coordinate multiple kinase activity by bringing them to one site.
Whether or not this phenomenon may be reproduced with other IFNg-resistant colon carcinoma cell lines is of particular interest, since colonic epithelium is physiologically exposed to PKC activators that enhance cytokine signalling in enterocytes during inflammatory responses within the intestinal mucosa [ 42 ] .