Example sentences for: pka-mediated

How can you use “pka-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Since (a) it is generally accepted that CD4 or CD8 are physically associated to the TCR in the course of T cell activation [ 17 18 ] and (b) it is well known that mitogen activated protein (MAP) kinase signaling is involved in the selection of the T cell repertoire [ 19 20 ] , the present study further proposes that the PKC and PKA-mediated signaling, which regulates TCR expression, can coordinately modulate the selection of CD4 +CD8 -and CD4 -CD8 +T cells during human intrathymic differentiation.


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