Example sentences for: pld

How can you use “pld” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In order to reduce PLD2 activity in SN56 cells, we sought to inhibit its expression.

  • The data are consistent with the report that a variant of PC12 cells also express exclusively PLD2 [ 18 ] and this expression is stimulated by nerve growth factor [ 18 ] , a treatment known to upregulate the cholinergic phenotype of PC12 cells [ 21 22 ] . PLD2 mRNA is abundant in many regions of the adult rodent central nervous system [ 6 23 ] , including cerebellum, frontal cortex, hippocampus, hypothalamus, midbrain, brainstem, striatum, and spinal cord [ 24 ] . The latter three regions are enriched with cell bodies of cholinergic neurons.

  • Since multiple receptor classes are affected by the pathophysiological processes of AD [ 41 ] , abnormal phosphorylation of α-synuclein may contribute to both altered α-synuclein turnover and abnormal regulation of PLD2 activity.

  • The cells were treated with a 25-mer antisense oligonucleotide at different concentrations and PLD2 mRNA levels were measured.

  • Transfection of PLD1 into SN56 cells resulted in increased PLD activity and ACh synthesis in a fashion similar to that observed in PLD2 transfectants (Fig.


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