Words similar to plcγ
Example sentences for: plcγ
How can you use “plcγ” in a sentence? Here are some example sentences to help you improve your vocabulary:
Biochemical analyses of Btk-deficient cells have suggested that PLCγ2 is a downstream substrate of Btk [ 8, 11].
No PLCγ2 phosphorylation was detected in unstimulated clones containing constitutive Syk activity (Figure 7D, lanes 4 and 7, upper panel).
In addition, we have found that kinase inactive Btk can reconstitute BCR-induced ERK MAPK activation, but not PLCγ2 phosphorylation (Tomlinson, Bolen and Johnston, unpublished data).
Upon treatment with 4-HT, a sustained PLCγ2 phosphorylation was induced in cells expressing WT Btk:ER that was not observed in cells expressing kinase inactive Btk:ER (Fig 2A).
The mechanism may involve stabilization by Btk of the PLCγ2 complex, or 'signalosome' [ 30], in an optimal conformation or subcellular location.
Loading...