Example sentences for: plcγ

How can you use “plcγ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In Fig 5Cwe have investigated the mechanism by measuring Btk:ER-induced apoptosis in parental and PLCγ2-deficient cells.

  • Apoptosis was detected in parental and PLCγ2-deficient cells in response to the control PMA and ionomycin treatment (Fig 5C).

  • Previous studies have shown that DT40 cells deficient for Btk and PLCγ2 have similar BCR signaling defects.

  • Additionally, the sustained PLCγ2 phosphorylation induced by Btk:ER is in agreement with the idea that Btk does not activate negative regulatory pathways that turn off the signal; rather it is Lyn that is thought to be largely responsible for this aspect of BCR signaling [ 15].

  • The slow Btk:ER kinetics are consistent with data derived from Btk-deficient cells, in which sustained BCR-induced PLCγ2 phosphorylation, calcium mobilization and MAPK activation are impaired, but the initial responses are relatively normal and appear to be driven by Syk activity (reviewed in reference [ 15]).


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