Example sentences for: plcγ

How can you use “plcγ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • An affinity purified anti-PLCγ2 antibody (SC406, Santa Cruz Biotechnology), was used for both immunoprecipitation and immunoblotting.

  • In Fig 5Awe found that Btk:ER activated ERK MAPK in parental but not in PLCγ2-deficient cells (lanes 2 and 7).

  • These data have led to the hypothesis that Btk co-operates with Syk in PLCγ2-dependent BCR signaling and that Btk functions as a signal duration modulator (reviewed in references [ 15, 16]).

  • A model has been proposed in which Btk controls calcium influx across the cell membrane by modulating PLCγ2 activity and thus IP3 levels [ 6, 29].

  • Since K430 is located on the smaller, NH 2 -terminal lobe of the kinase domain, whereas R525 is part of the larger, COOH-terminal lobe, it is possible that the two mutations differentially affect the capacity of kinase inactive Btk to function as an adapter in the activation of PLCγ2.


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