Words similar to plcγ
Example sentences for: plcγ
How can you use “plcγ” in a sentence? Here are some example sentences to help you improve your vocabulary:
In Fig 5Cwe have investigated the mechanism by measuring Btk:ER-induced apoptosis in parental and PLCγ2-deficient cells.
Apoptosis was detected in parental and PLCγ2-deficient cells in response to the control PMA and ionomycin treatment (Fig 5C).
Previous studies have shown that DT40 cells deficient for Btk and PLCγ2 have similar BCR signaling defects.
Additionally, the sustained PLCγ2 phosphorylation induced by Btk:ER is in agreement with the idea that Btk does not activate negative regulatory pathways that turn off the signal; rather it is Lyn that is thought to be largely responsible for this aspect of BCR signaling [ 15].
The slow Btk:ER kinetics are consistent with data derived from Btk-deficient cells, in which sustained BCR-induced PLCγ2 phosphorylation, calcium mobilization and MAPK activation are impaired, but the initial responses are relatively normal and appear to be driven by Syk activity (reviewed in reference [ 15]).
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