Words similar to plc
Example sentences for: plc
How can you use “plc” in a sentence? Here are some example sentences to help you improve your vocabulary:
The fact that U73343, which has essentially no effect on PLC at the concentrations employed [ 14 25 26 27 ] , is more potent than U73122 on MTX-induced responses, clearly shows that the effect of these agents is unrelated to inhibition of PLC.
Conglomeratization: Book publishing is dominated by seven media conglomerates : Paramount (Simon & Schuster), News Corp. (HarperCollins), Bertelsmann AG (Bantam Doubleday Dell), Advance Publications (Random House), Time Warner (Little, Brown), Pearson PLC (Viking Penguin), and Holtzbrinck (Holt).
It is however, well established that MTX causes the hydrolysis of phosphoinositides in some cell types, presumably via activation of phospholipase C (PLC) [ 12 13 ] . Activation of PLC by MTX appears to be indirect resulting as a consequence of increased [Ca 2+] i . These results suggest that PLC may be involved in activation of COP and/or in the cytolysis phase of MTX action.
And Wang [ 16 ] reported that U73343 suppressed elevation of [Ca 2+] i in neutrophils challenged with FMLP in the presence, but not the absence, of extracellular Ca 2+Both reports are consistent with a lack of effect of U73343 on receptor-mediated activation of PLC and a direct inhibitory effect on Ca 2+influx pathways in these cells.
Thus, the initial purpose of the present study was to determine the role of PLC in MTX-induced cell death.