Words similar to plc

Example sentences for: plc

How can you use “plc” in a sentence? Here are some example sentences to help you improve your vocabulary:

To test the hypothesis that MTX-induced cell death requires PLC, the effect of U73122, a specific inhibitor of PLC was examined.
However, both compounds have been shown to produce non-specific effects presumably unrelated to inhibition of PLC [ 15 16 17 18 19 20 ] . The results of the present study show, that both U73122 and U73343 inhibit MTX-induced change in [Ca 2+] i , ethidium uptake, and LDH release in BAECs.
This compound selectively inhibits mammalian PLC, but has no direct effect on bacterial PLC, bacterial or mammalian phospholipase A 2 or adenylyl cyclase [ 14 ] . U73343, a structural analogue of U73122 that differs by only one double bond, has no direct effect on PLC and is commonly used as a negative control.
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It is however, well established that MTX causes the hydrolysis of phosphoinositides in some cell types, presumably via activation of phospholipase C (PLC) [ 12 13 ] . Activation of PLC by MTX appears to be indirect resulting as a consequence of increased [Ca 2+] i . These results suggest that PLC may be involved in activation of COP and/or in the cytolysis phase of MTX action.