Words similar to plc-γ

Example sentences for: plc-γ

How can you use “plc-γ” in a sentence? Here are some example sentences to help you improve your vocabulary:

Finally, the presence of a highly active Syk enzyme in cells was insufficient for downstream signal transduction as evidenced by a lack of change in global tyrosine phosphorylation, phosphorylation of PLC-γ2 or enhanced spontaneous or induced apoptosis.
Recent data argue that Itk interacts directly with Slp-76 and Grb2 to participate in a LAT-nucleated T cell signaling complex involved in PLC-γ activation [ 5, 29].
The importance of the Tec kinases in antigen receptor signaling was first demonstrated by the observation that mutations in BTK result in the human disease X-linked agammaglobulinemia (XLA) and the murine counterpart X-linked immunodeficiency ( xid ). These severe B cell immunodeficiencies are characterized by diminished numbers of mature B cells and reduced immunoglobulin levels associated with impaired PLC-γ activation and Ca ++mobilization in response to surface IgM stimulation (sIgM) [ 8, 9, 10, 11].
Furthermore, we have found that combined mutation of Rlk and Itk leads to profound defects in TCR signaling associated with impaired activation of PLC-γ [ 20].
In contrast, PLC-γ was not found in the RAFT fraction constitutively, but a portion became inducibly associated with RAFTs upon activation.