Example sentences for: phosphorylated

How can you use “phosphorylated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A heterooligomeric SCF Pop1p-Pop2pcomplex mediates polyubiquitylation of phosphorylated Rum1p.

  • Phosphorylated eIF2α competitively inhibits the guanine nucleotide exchange factor eIF-2B, which is responsible for the recycling of eIF2 by catalyzing the conversion of eIF2-GDP to the active form eIF2-GTP [ 36 ] . Thus the overall initiation of translation is inhibited when eIF2α becomes phosphorylated.

  • Neurogranin has been shown to be phosphorylated by PKCγ, and this phosphorylation is greatly decreased in PKCγ knockout mice, suggesting neurogranin is a PKCγ-specific substrate [ 9 ] . Evidence that strongly suggests the phosphorylation of neurogranin plays an important role in neural plasticity comes from the studies that demonstrated neurogranin knockout mice show essentially the same deficits in behaviors related to learning and memory as that of the PKCγ knockout mice [ 10 ] . Neurogranin is not only a substrate of PKCγ, but also plays a important role in regulating PKC signaling [ 11 ] . Interstingly, PKCγ knockout mice demonstrate reduced neuropathic pain [ 12 ] . Similar to neurogranin, we found that a calmodulin-binding, vesicle-associated, CAM kinase IV-like protein is highly expressed and enriched in the superficial layer of the dorsal spinal cord.

  • However, co-expression of the Src KM/Cas(SD) chimera along with a SH2 mutant of v-crk demonstrated that an intact v-crk SH2 domain is required for association with the tyrosine phosphorylated Src KM/Cas(SD) (Fig.

  • The phospho-MAPK antibody recognizes dual phosphorylated Erk1 and Erk2 at Thr202/Tyr204.


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