Example sentences for: phosphorylating

How can you use “phosphorylating” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TGFβ signals through a heteromeric receptor complex of type II and type I receptor serine-threonine kinases, which activates the downstream Smad signal transduction pathway [ 7 ] . After TGFβ binding to the receptor complex, the TGFβ type II receptor kinase phosphorylates TGFβ type I receptor which inititates the downstream response by phosphorylating receptor-regulated Smads (R-Smads), such as Smad2 and Smad3.

  • We are exploring whether this occurs from enhanced translation of cyclin D 1 message and/or decreased degradation of cyclin D 1 protein and whether other D-type cyclins may be involved in phosphorylating pRb in HIVAN.

  • Cdc5 also helps to activate the MEN by directly phosphorylating and disabling Bfa1 [ 29 ] , which is thought to inhibit Tem1 by serving as a GTPase-activating protein.

  • Indeed, Cdc5 and the Xenopus polo-like kinase Plx1 reduced the binding affinity between recombinant Cdc14 and Net1 by phosphorylating Net1, and dislodged both Cdc14 and Sir2 from the RENT complex in vitro .

  • Co-localization of a MHCK with its apparent substrate does not imply that the kinase, in vivo, is actively phosphorylating its substrate.


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