Words similar to phosphorylate
Example sentences for: phosphorylate
How can you use “phosphorylate” in a sentence? Here are some example sentences to help you improve your vocabulary:
Signaling by the IGF-IR has been studied in many different cell types and is important for proliferation, survival, motility, adhesion, transformation, tumor formation and metastasis [for reviews see refs [ 31 32 ] ]. The receptor can directly phosphorylate the insulin receptor substrate 1 (IRS-1) and Shc proteins in the intact cell causing activation of PI-3Kinase and ras signaling [ 33 ] . More recently, it has been shown that the IGF-IR signals via the Gβγ subunits of the heterotrimeric Gi complex to stimulate PI-3Kinase and ras, and also activates the JAK/Stat pathway to cause phosphorylation of Stat3 [ 34 35 ] .
Mutations in the E2 enzyme Cdc34 or in any of the SCF Cdc4components (Cdc53/Cul1, Skp1 and Cdc4) arrest cells at the G1/S transition because of a failure to degrade the cyclin-dependent kinase (CDK) inhibitor Sic1 [ 3 ] [ 4 ] . In a wild-type situation, G1 cyclin/CDK complexes phosphorylate Sic1 at the end of G1.
One of the effects of PKR is to phosphorylate the α subunit of the general translation initiation factor eIF-2, which constitutes a major mechanism for global translation arrest.
This study demonstrates that GSK3β, but not GSK3α, can directly phosphorylate serine 33 of p53 when serine 37 of p53 is already phosphorylated.
A double-weight, solid-headed 'phosphorylate' arrow represents the transfer of phosphate groups by the kinase site of Cdk4 to increase occupancy of the retinoblastoma protein (RB) phosphorylation site.