Words similar to phosphorylate
Example sentences for: phosphorylate
How can you use “phosphorylate” in a sentence? Here are some example sentences to help you improve your vocabulary:
Two molecular loci recently have been implicated as potential modulators of GnRH receptor signaling: one is the receptor itself [ 23 ] , and the other is the G protein that transduces the signal generated by binding of the receptor to its agonist [ 9 ] . With respect to the former locus, G protein coupled receptor kinases (GRKs) act in an agonist-specific manner to phosphorylate intracellular regions of the receptor thus permitting β arrestin binding that sterically inhibits G protein association with the receptor [ 1 45 ] . We have reported previously that experimental expression of GRKs in GnRH receptor-expressing heterologous cells (COS-1) suppressed GnRH-stimulated IP 3 production, and that co-expression of GRK2 and β-arrestin 2 suppressed GnRH receptor signaling more than that of either alone [ 23 ] . Stronger evidence that the GRK/β arrestin paradigm may play a role in regulating GnRH receptor signaling is our recent finding that adenovirus-mediated gene transfer of GRK2 into normal pituitary gonadotropes suppressed GnRH-stimulated LH secretion and IP 3 production [ 31 ] . However, no evidence has been presented for a direct interaction between β-arrestin and the GnRH receptor.
The MEK1/ERK pathway regulates cPLA 2 and ERKs phosphorylate cPLA 2 on Ser 505.
In fig 4, GSK3β kinase activity was monitored by immunoprecipitating GSK3β and then measuring the ability of the immunoprecipitated protein to phosphorylate a specific GSK3β peptide substrate.
To examine the ability of Syk from cells that expressed (K395A/3F)Syk to phosphorylate an exogenous Syk target, c3b-GST was added to the Syk ICKA (Figure 4, lower panels).
However, unlike PI-3 kinases, PIKKs are not known to phosphorylate lipids but do possess protein kinase activity.
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