Words similar to phosphorothioate

Example sentences for: phosphorothioate

How can you use “phosphorothioate” in a sentence? Here are some example sentences to help you improve your vocabulary:

Phosphorodithioate 6c was a less effective inhibitor ( K i = 8600 nM, not shown in Tables) than corresponding phosphate 6a and phosphorothioate 6b and, as demonstrated in Tables 1and 2, the phosphorothioate congener of every compound made as a phosphate and a phosphorothioate had a lower K i value.
The phosphorothioate analogs, 5b and 6b, bound approximately 10 and 75 times better to Fhit than 1 . Thus, conservation of bond-lengths between adenylate moieties of 1 , 5 and 6 is conducive to binding Fhit.
Earlier, Blackburn and co-workers made "supercharged" methane-trisphosphonic acid AppppA analogs containing a central carbon from which three adenylate or phosphate moieties are bonded [ 15 ] . In work presented here, tripodal inhibitors 15a and 17a showed, respectively, micromolar and submicromolar efficacies while the phosphorothioate counterparts 15b and 17b showed 100 nM efficacy.
Because phosphorothioate analogs of 5 and 6 were better inhibitors than the corresponding phosphates, phosphorodithioate analog 6c was prepared together with five additional compounds as phosphates and phosphorothioates.
The contribution of particular P-chiral phosphorothioate stereoisomers to inhibition has not been examined.