Words similar to phosphorothioadenosyl

Example sentences for: phosphorothioadenosyl

How can you use “phosphorothioadenosyl” in a sentence? Here are some example sentences to help you improve your vocabulary:

We presume that compounds 6b , 12b and 13b with 2, 3 or 4 identical CH 2 -phosphorothioadenosyl groups can present a manganese bound 6b -like complex to Fhit in a similar manner.
A series of compounds 2-6 were synthesized and evaluated for Fhit inhibition that link two 5'- O -phosphorothioadenosyl or AMP groups with five reagents ranging in size from ethylene glycol to meso -erythritol.
Thus, while the simplest compound 6b was initially rendered less inhibitory by modification because its central hydroxyl was important for inhibition, addition of one or two CH 2 -phosphorothioadenosyl groups restored inhibition.
Compound 12b, which one would expect to bind Fhit with bulky phosphorothioate and phosphorothioadenosyl groups interfering with putative effector binding, may consequently prove to be antagonistic to Fhit function.
On the basis of observations [ 12 13 ] discussed above, one would expect AppppA with two phosphorothioadenosyl substituents to be a slow substrate with a relatively low K m . However, carbon in place of the β phosphorus (for example in 6b ) would make the leaving group the alkoxide - OCH 2 -CH(OH)-CH 2 O-phosphorothioadenosyl rather than α-thio ATP.