Example sentences for: phosphorolysis

How can you use “phosphorolysis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutations that greatly diminish the enzymatic activity of huAPE1 do not affect, and may even increase binding to damaged DNA, while non-specific DNA binding remains low [ 16 18 ] . Further, mutations that have little effect on APE activity in vitro prevent complementation of DNA repair deficient E. coli . As seen with other DNA repair enzymes [ 19 ] , specificity determining residues, as yet unidentified for APEs, must be distinct from those involved in phosphorolysis.

  • Overall, the pattern of protein contacts to the cleavage site, the area 5' of the cleavage site, and the 3' end of the opposite strand are common to both proteins, suggesting that the functions of forming the substrate complex and the actual phosphorolysis are similar in both proteins.


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