Example sentences for: phosphorolytic

How can you use “phosphorolytic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The endonuclease activity of DNase 1 is reduced many fold by integrating this loop from E. coli exonuclease III, but the mutant cleaves at abasic sites in DNA with low efficiency [ 29 ] . Thus additional residues in the APEs control specificity while still allowing a reasonable rate of phosphorolytic cleavage.

  • These molegos could in turn be functionally annotated by comparing the DNA binding profile of APE1 with that of the less specific nuclease DNase 1. This analysis indicated that residues binding 3' to the site of phosphorolytic cleavage control the substrate specificity of APE1.

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