Example sentences for: phosphatases

How can you use “phosphatases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).

  • In addition to acting as a scaffolding protein for kinases and phosphatases, gravin forms a dynamic complex with beta-adrenergic receptors [ 51 ] . The same report also showed that the association of beta-adrenergic receptors with PKA could be blocked by the Ht31 peptide, which blocks AKAP-kinase binding.

  • The marine toxin okadaic acid (OA), in particular, inhibits the PP2A class of phosphatases at sub-nanomolar concentrations (IC50 ~ 0.05 nM) and the PP1 class in the low nanomolar range (IC50 ~ 5-45 nM).

  • We also analysed for tyrosine-phosphorylated proteins in the insoluble fraction of cells treated with pervanadate (PV), a potent inhibitor of tyrosine phosphatases, extracted with 0.5% detergent.

  • Genes encoding practically all the solo versions of the HNOB domain occur in the same predicted operon as a histidine kinase or a GGDEF domain (diguanylate cyclase) [ 33 34 35 ] . In some cases these operons also encode receiver domain proteins of the two component systems, PP2C phosphatases or cyclic diguanylate phosphodiesterases (Fig.


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