Example sentences for: phosphatases

How can you use “phosphatases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, the characteristic IC 50 values for OA fall in the range: PP2A, 1-5 nM, PP1, 20-80 nM, whereas PP2B is highly resistant to both [ 2 3 7 ] . In contrast, tautomycin affects PP1 and PP2A nearly equally, but fails to inhibit other phosphatases [ 8 ] .

  • The SAPNYC motif of PPP enzymes is essential for OA-binding, and is found in all OA-sensitive phosphatases including PP1, PP2A, and PP5 [ [ 25 27 28 ] , and references therein].

  • When these inserts were omitted from the alignment, the rest of the sequence showed significant similarity with PP1 phosphatases [ 12 ] . Clearly, further studies are needed to identify the PPα protein and characterize its potentially interesting identity.

  • Furthermore, in humans, it is now clear that there are four isoforms of PP1 [PP1α, PP1δ, PP1γ 1 and PP1γ 2 [ 11, 12, 13], two isoforms of PP2A (PP2A α and PP2Aβ [ 14, 15]) and four structurally related phosphatases, PP4 [ 16], PP5 [ 17, 18], PP6 [ 19] and PP7 [ 20].

  • This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).


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