Words similar to phosphatases
- phooey
- phorbol
- phoretics
- phoretix
- phosphatase
- phosphatase-conjugated
- phosphatase-coupled
- phosphatase-labelled
- phosphatase-mediated
- phosphatased
- phosphatases
- phosphate
- phosphate-accepting
- phosphate-binding
- phosphate-buffered
- phosphate-conjugated
- phosphates
- phosphatidyl-
- phosphatidylcholine
- phosphatidylinositol-
Example sentences for: phosphatases
How can you use “phosphatases” in a sentence? Here are some example sentences to help you improve your vocabulary:
The marine toxin okadaic acid (OA), in particular, inhibits the PP2A class of phosphatases at sub-nanomolar concentrations (IC50 ~ 0.05 nM) and the PP1 class in the low nanomolar range (IC50 ~ 5-45 nM).
This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).
We also analysed for tyrosine-phosphorylated proteins in the insoluble fraction of cells treated with pervanadate (PV), a potent inhibitor of tyrosine phosphatases, extracted with 0.5% detergent.
Mammalian protein phosphatase 5 (PP5) and its homolog protein phosphatase T1 (Ppt1p) from the yeast Saccharomyces cerevisiae contain a catalytic domain structurally related to the catalytic subunits of PP1, PP2A and PP2B, and an N-terminal domain consisting of multiple tetratricopeptide repeats (TPRs) not found in other members of this family of phosphatases [ 1 2 3 ] . Homologs have also been identified in Xenopus laevis [ 4 ] , Neurospora crassa [ 5 ] , Drosophila melanogaster [ 6 ] , Trypanosoma brucei [ 7 ] , Plasmodium falciparum [ 8 9 ] , and cauliflower [ 10 ] , and homologs for Caenorhabditis elegans, Schizosaccharomyces pombe and Arabidopsis thaliana are predicted (accession number CAB60937, CAA17690 and AAD21727, respectively).
PP2 is a serine/threonine phosphatase which dephosphorylates JNK during inflammatory cell signaling [ 19 ] , while MKP5 is a member of the dual specificity phosphatase family which selectively dephosphorylates stress activated MAP kinases including JNK [ 20 ] . The overexpression of these two phosphatases might contribute in part to the resistance of HL60/TLK286 by impairing the activity of JNK.
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