Words similar to phosphatases
- phooey
- phorbol
- phoretics
- phoretix
- phosphatase
- phosphatase-conjugated
- phosphatase-coupled
- phosphatase-labelled
- phosphatase-mediated
- phosphatased
- phosphatases
- phosphate
- phosphate-accepting
- phosphate-binding
- phosphate-buffered
- phosphate-conjugated
- phosphates
- phosphatidyl-
- phosphatidylcholine
- phosphatidylinositol-
Example sentences for: phosphatases
How can you use “phosphatases” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is to be mentioned that among all the Ser/Thr phosphatases, PP1 has been subjected to the most extensive structure-function analysis [ 19 20 21 22 23 24 25 26 ] . In fact, it was one of the first phosphatases for which the three-dimensional structure was solved [ 26 27 ] . A representative alignment in Fig.
This GPCR-mediated regulation of ion channels also depends on the coordination and parallel regulation of protein tyrosine kinase and protein tyrosine phosphatase activities [ 24 ] . GPCRs can also interact with the growing family of PDZ domain-containing proteins [ 25 ] . All of these relationships are reflected in our study by the strong correlation between 7 transmembrane receptors (rhodopsin family) (PF00001), protein kinases (PF00069), protein tyrosine phosphatases (PF00102), ion transport proteins (PF00520), and PDZ domain proteins (PF00595).
Under conditions favoring proliferation, the phosphorylation of pRB via cyclin-dependent kinases (CDKs) in mid-to-late G 1 phase results in liberation of E2F and other pRB-bound transcription factors, which then activate the transcription of S-phase genes [ 19 ] . In late M phase, pRB returns to its growth suppressive, hypophosphorylated form due to the action of a pRB-directed protein phosphatase belonging to the type 1 class of serine/threonine protein phosphatases [ 11 20 21 ] .
Budding yeast lacking PPT1 do not exhibit obvious growth defects or detectable phenotypes [ 2 ] . Disruption of PPT1 together with one of the other known phosphatases in budding yeast also reveals no obvious phenotype [ 23 ] . Thus, if Ppt1p has an essential function in S. cerevisiae , more than one other phosphatase can also carry out this role.
First, PfPP5 contained the catalytic core found in all Ser/Thr phosphatases of the PPP family, including the signature motifs such as GDXHGQ, GDFVDRG, RGNHE, HGLL, and SAPNYCD, to name a few [ 22 23 ] . Site-directed mutagenesis and structural studies in PP 1 and PPλ have previously established the roles of specific amino acid residues in these domains in the various aspects of catalysis, such as metal ion binding, phosphate recognition, and co-ordination of water molecules [ 24 25 26 ] .
Loading...