Example sentences for: phorbol

How can you use “phorbol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phorbol esters are often used as activators of PKC to investigate the role of the kinase in cellular functions [ 1 ] . Accumulating lines of evidence indicates that PMA plays a complex role in regulation of cellular function, including PKC-dependent [ 18 19 20 ] and PKC-independent ways [ 23 24 21 ] . In the present results, PMA inhibited slow membrane depolarization and action potentials in response to glucose stimulation (Fig.

  • The identification of the regulatory components of the ectodomain shedding machinery have been long-sought in other studies employing phorbol esters to stimulate shedding of sAPP α or TGFα [4,35,36,37].

  • phorbol 12-myristate 13-acetate PMA

  • There are two possible explanations for the PKC-independent activation of K ATP by phorbol esters: 1) phorbol esters may increase K ATP activity in an intracellular ATP-independent manner and 2) phorbol esters may reduce sensitivity of K ATP to ATP.

  • Louis, MO) and phorbol 12-myristate 13-acetate was from Calbiochem (La Jolla, CA).


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