Words similar to phorbol

Example sentences for: phorbol

How can you use “phorbol” in a sentence? Here are some example sentences to help you improve your vocabulary:

LPS stimulation of macrophages is known to involve the activation of protein phosphorylation by kinases as well as the activation of nuclear transcription factors such as NF-kappaB [ 10 11 12 13 ] . The activation of protein kinase C (PKC) by diacylglycerol is also a key event in LPS macrophage activation [ 8 ] . In vitro experiments have shown that the secretion of TNF-alpha and IL-1-beta by LPS-stimulated monocytes is dependent upon PKC activation [ 13 14 ] . In this study, we also determined if phorbol myristate acetate (PMA) activation of PKC also enhanced CEES toxicity.
Effect of phorbol ester on the oxidative activities of lysosomes
Recently, we reported that phorbol ester inhibited Ca 2+influx through PKC-dependent and PKC-independent pathways [ 21 ] . In the present study, we further evaluated the non-PKC mechanism of PMA action on β-cell electrical excitation by using patch-clamp techniques.
Munc-13 has recently been implicated as a phorbol target in regulated shedding [38].
In addition, other recent studies have shown that the membrane phospholipid phosohatidylinositol-4,5-bis-phosphate (PIP 2 ) reduces sensitivity of K ATP to ATP, and therefore, activates K ATP [ 32 33 34 ] . To our knowledge, this is the first report of regulation of K ATP activity by phorbol ester in rat β-cells.