Example sentences for: phorbol

How can you use “phorbol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 1ACh, acetylcholine; ARF, ADP-ribosylation factor; DAG, diacylglycerol; G3PDH, glyceraldehyde 3-phosphate dehydrogenase; MAChR, muscarinic acetylcholine receptor; PA, phosphatidic acid; PC, phosphatidylcholine; PIP 2 , phosphatidylinositol 4, 5-bisphosphate; PKC, protein kinase C; PLD, phospholipase D; PMA, phorbol 12-myristate 13-acetate; PP, phosphatidylpropanol; ROS, reactive oxygen species; TLC, thin layer chromatography.

  • The tumor promoter phorbol myristate acetate (PMA) has been shown to activate the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase and initiate the oxidative burst response in various phagocytes, including neutrophils and the macrophage-like cell line J774A.

  • PMA, a phorbol ester, activates PKC and has previously been shown to activate SL-1 [ 40 ] . It appears that mesothelin is activated by Wnt-1, which can be mimicked by LiCl, and that SL-1 is activated by Wnt-5a in a beta-catenin-independent manner, which can be mimicked by activating PKC.

  • The identification of the regulatory components of the ectodomain shedding machinery have been long-sought in other studies employing phorbol esters to stimulate shedding of sAPP α or TGFα [4,35,36,37].

  • Actinomycin D, roscovitine, phorbol ester and lipopolysaccharide (LPS) were purchased from Calbiochem.


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