Example sentences for: phosphatase

How can you use “phosphatase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, in the Jurkat lymphoma cell line, which is deficient in the inositol phosphatase PTEN, Itk is constitutively associated with the membrane [ 36].

  • When assayed for phosphatase activity in vitro, the trypsin-digested PfPP5 indeed behaved like ΔTPR-PfPP5 in that it was about 3-fold more active than the full-length enzyme and was not activated by arachidonic acid any further (Fig.

  • In order to establish whether PTEN protein phosphatase activity could be reliably measured in vitro, we first transfected PTEN-negative U87 cells with an expression vector harboring PTEN cDNA.

  • In addition to its known lipid phosphatase activity, PAP2b/VCIP also mediate cell-cell interactions [ 31 ] .

  • Under conditions favoring proliferation, the phosphorylation of pRB via cyclin-dependent kinases (CDKs) in mid-to-late G 1 phase results in liberation of E2F and other pRB-bound transcription factors, which then activate the transcription of S-phase genes [ 19 ] . In late M phase, pRB returns to its growth suppressive, hypophosphorylated form due to the action of a pRB-directed protein phosphatase belonging to the type 1 class of serine/threonine protein phosphatases [ 11 20 21 ] .


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