Example sentences for: phosphates

How can you use “phosphates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These observations suggest that the CYTH domains are likely to be domains specialized to bind nucleotides and other organic phosphates.

  • It has been reported that the amino group serves as one of VO 2+equatorial ligands in CF 1 -ATPase [ 21 ] , pyruvate kinase [ 19 20 ] , AdoMet synthetase [ 17 18 ] , and carboxypeptidase [ 16 ] . Thus one amino group from lysine, one carboxyl group from aspartate or glutamate, and two oxygens from the phosphates of ADPNP serve as the equatorial ligands of sCD39 bound VO 2+in the presence of ADPNP.

  • We compared the conserved ATP binding site in kinesins (FAYGTGSGKT) and two other sequences involved in interacting with nucleotide phosphates (NXXSSRSH and VDLAGSE) [ 42, 43].

  • The middle histidine of the histidine triad (His96 in human Fhit), which is critical for hydrolysis of ApppA by Fhit [ 14 16 ] , is not necessary for tumor suppression [ 17 18 ] . Nonetheless, wild-type and His96Asn forms of Fhit are saturated by ApppA in the low micromolar range and form stable complexes with non-hydrolyzable ApppA in which two ApppA analogs are bound per Fhit dimer and all phosphates cluster on one surface of the protein [ 16 ] . These observations suggested that Fhit-substrate complexes may be the active, signaling form of Fhit and that the function of the catalytically essential histidine may be to terminate the lifetime of signaling complexes [ 16 ] .

  • O -phosphates and phosphorothioates to short-chain polyols [ 14 ] , we evaluate four inhibitor parameters and obtain compounds, inhibitory constants for which are as much as 70-fold lower than natural substrates.


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