Example sentences for: phosphates

How can you use “phosphates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has been reported that the amino group serves as one of VO 2+equatorial ligands in CF 1 -ATPase [ 21 ] , pyruvate kinase [ 19 20 ] , AdoMet synthetase [ 17 18 ] , and carboxypeptidase [ 16 ] . Thus one amino group from lysine, one carboxyl group from aspartate or glutamate, and two oxygens from the phosphates of ADPNP serve as the equatorial ligands of sCD39 bound VO 2+in the presence of ADPNP.

  • The calculated g || and A || values that best matched the experimental values for species D2 suggest that one hydroxyl group and three oxygens derived from carboxyl groups and phosphates are the equatorial ligands of bound VO 2+-ADP.

  • O -phosphates and phosphorothioates to short-chain polyols [ 14 ] , we evaluate four inhibitor parameters and obtain compounds, inhibitory constants for which are as much as 70-fold lower than natural substrates.

  • When transfected into Chinese hamster ovary (CHO) cells, activation of the SPR results in an increase in intracellular Ca ++[ 5], accumulation of inositol phosphates and cAMP formation [ 6].

  • Organic phosphate compounds are the central metabolites of all biological systems [ 1 2 ] . Some are the basic building blocks of nucleic acids, some like ATP and GTP, are additionally, cellular energy stores, others like cAMP or cGMP are messengers in signal transduction, and, yet others, such as FAD, NAD, thiamine phosphates and pyridoxal phosphate are cofactors for a range of enzymes [ 1 2 ] . Protein domains belonging to a relatively small set of structural folds are known to bind or catalyze reactions that utilize these organic phosphate compounds (see SCOP database: http://scop.mrc-lmb.cam.ac.uk/scop/) [ 3 4 ] . Several of these folds trace back to some of the earliest phases of the evolution of the protein world, and participate in a wide range of disparate biological functions in extant proteins [ 4 5 ] . Some folds, such as the P-loop fold, the Rossmann fold and the Hsp70-like fold, have been well studied, and comprise mainly of dedicated nucleotide binding or hydrolyzing proteins [ 6 7 8 9 ] . Others, such as the palm-domain, which is found in adenylyl cyclases and various nucleic acid polymerases, belong to more generalized protein folds that contain representatives with diverse biochemical activities [ 4 10 11 ] . Current availability of extensive genome sequence data, allows one to identify less numerous, nevertheless biological important organic phosphate-binding domains that may have previous eluded detection.


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