Example sentences for: phosphatidylinositol-

How can you use “phosphatidylinositol-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PI-3Kinase activity is acutely regulated and a number of isoforms have been cloned that are activated in response to various stimuli [ 4 ] . The major phosphatidylinositol-3-phosphate phosphatase in cells is the tumor suppressor PTEN [ 5 6 ] . This protein has a tonic inhibitory effect on PI-3Kinase signaling by reversing the 3'-phosphorylation.

  • Phosphatidylcholine, phosphatidylinositol, and phosphatidylserine were from Avanti Polar Lipids (Alabaster, AL); phosphatidylinositol-4,5-bisphosphate and phosphatidylinositol-4-phosphate were from Calbiochem (San Diego, CA); and phosphatidylinositol-3-phosphate was from Matreya, Inc. (Pleasant Gap, PA).

  • PIP3: Phosphatidyl-3,4,5-triphosphate; DMEM: Dulbecco's Modified Eagle's Medium; PI-3Kinase: phosphatidylinositol-3-kinase; MAPK: mitogen-activated protein kinase; IGF: insulin-like growth factor; PTEN: phosphatase and tensin homolog deleted from chromosome 10; SOS: son-of-sevenless ras exchange factor; ASK: apoptosis stimulating kinase; FKHR: forkhead related protein; cFLIP: cellular FLICE interacting protein; BSA: bovine serum albumin; TBS: tris buffered saline; PVDF: polyvinylidene difluoride

  • The gene product of PTEN ( phosphatase and tensin homolog deleted from chromosome 10) is a lipid phosphatase that reverses the activities of phosphatidylinositol 3-kinase (PI3K) by dephosphorylating the D3 position of its lipid products, phosphatidylinositol-3, 4 bis-phosphate (PtdIns(3,4)P2), phosphatidylinositol-3,5 bis-phosphate (PtdIns(3,5)P2), and 3,4,5-tri-phosphate (PtdIns(3,4,5)P3) [ 2, 3], the elevated levels of which are linked to the transforming ability of PI3K [reviewed in ref.

  • Selected transcripts identified by microarray analysis, including β-actin, spectrin and phosphatidylinositol-4-kinase (PI4K), were subsequently confirmed by semi-quantitative RT-PCR (Fig.


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