Example sentences for: pgs

How can you use “pgs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The effects of PGs on cell proliferation and collagen production have been widely studied in different cell types [ 13 14 15 16 17 26 ] . TXA 2 has been studied extensively because of its apparent role in atherosclerosis, due to its prothrombotic and mitogenic activities on vascular smooth muscle cells [ 15 16 ] . These mitogenic effects are potentiated by growth factors [ 15 16 27 28 ] . In vascular smooth muscle cells TXA 2 stimulates synthesis of bFGF and increases the expression of the proto-oncogenes c-fos , c-myc , and egr-1 , which are associated with entry into the cell growth cycle [ 15 ] . In addition, TXA 2 increases proliferation of fibroblasts [ 13 ] and smooth muscle-like glomerular mesangial cells [ 14 ] .

  • The IgG2a antibody responses to both human and mouse PGs were lower in these mice than in wild-type mice (Fig.

  • However, PG E 2 production was affected relatively little compared to the other PGs.

  • Many cell types, including lung fibroblasts, contain cyclooxygenase (COX), a proximal enzyme in prostanoid production, and can generate prostanoids [ 19 ] . It has been previously reported that IPF lung fibroblasts have decreased COX-2 expression compared to normal lung fibroblasts and, hence, have decreased PGE 2 production [ 12 20 21 ] . Because of these findings and the fact that PGs are important fibroblast regulators, we sought to investigate whether abnormalities in COX-2 expression could be associated with an altered balance between profibrotic and antifibrotic PGs.

  • Thus IDO overexpression resulted in an increase in PG E 2 relative to the other PGs.


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