Example sentences for: ph-

How can you use “ph-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Upregulation of p53 and WOX1 contributes, in part, to the PH-20-enhanced cytotoxic function of TNF [ 9 10 23 ] . WOX1 is a p53-binding protein.

  • Whether these TGF-β1-induced proteins restrict the ability of PH-20 to increase TNF cytotoxicity is unknown.

  • As summarized in Figure 1, PH-20 induces the expression of proapoptotic p53 and WOX1 [ 9 10 ] and downregulates antiapoptotic matrix inter-α-inhibitor [ 9 ] , thereby enhancing TNF susceptibility in L929 cells.

  • Although it is tempting to conclude that the pH- and heat-resistent dimerization we observe with VR1 results from a covalent interaction, we cannot rule out other explanations such as strong hydrophobic interactions.

  • In contrast, TGF-β1 protects L929 cells from TNF cytotoxicity by upregulating the expression of antiapoptotic TIAF1, TIF2 and a novel matrix protein [ 11 12 13 14 ] . TGF-β1 blocks PH-20-increased TNF susceptibility [ 15 ] . Likewise, PH-20 inhibits TGF-β1-induced TNF-resistance [ 15 ] . TGF-β1 suppresses PH-20-mediated ERK activation [ 16 ] ; however, the ERK activation is not related with PH-20-increased TNF susceptibility in L929 cells [ 15 ] . Whether the proapoptotic p53 and WOX1 block the function of antiapoptotic TIAF1 and TIF2 is not known.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast