Example sentences for: orthologous

How can you use “orthologous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The species compared here, S. cerevisiae and S. pombe , are much more closely related than S. cerevisiae and C. elegans , and orthologous proteins are likely to be more reliably inferred between the closely related genomes.

  • The orthologous rat mRNA has not been cloned yet, which is reflected by the more than 2.5 million mouse EST sequences present in dbEST, compared to only 351,827 ESTs for the rat.

  • An orthologous group of proteins typified by human Sec14L1, which is conserved in all animals, has, in addition to the carboxy-terminal fusion of the Sec14p and GOLD domains, a previously unrecognized, conserved amino-terminal domain (Figures 2, 3).

  • COGs containing 60 or more members were excluded because of potential uncertainty of orthologous relationship between members of such large groups [ 18].

  • As the framework for this analysis, we used the database of clusters of orthologous groups (COGs) of proteins [ 18, 19], which contains sets of orthologous proteins and domains from complete microbial genomes (32 genomes at the time of this analysis; see Materials and methods).


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