Words similar to orthologous

Example sentences for: orthologous

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However, a principle of phylogenomics is that orthologous sequences (that diverged by speciation) are more likely to conserve protein function than paralogous sequences (that diverged by gene duplication).
Specifically, the r 2value indicates that less than 1% of the variation in substitution rates between orthologous proteins is explained by the variation in the number of protein-protein interactions.
A subset of probable orthologous pairs that met the criteria used for identification of paralogs (score density of 1.5 bit/position and aligned over at least 95% of their lengths) was selected.
Symmetrical best hits in these BLAST searches (expectation value ≤ 10 -3) were taken to be orthologs [ 20 ] . Pairs of orthologous proteins were aligned using the ClustalW program [ 21 ] and their substitution (evolutionary) rates were calculated using the gamma distance correction [ 22 ] . The data on protein-protein interactions for the
The species compared here, S. cerevisiae and S. pombe , are much more closely related than S. cerevisiae and C. elegans , and orthologous proteins are likely to be more reliably inferred between the closely related genomes.