Words similar to orthologues
Example sentences for: orthologues
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Figure 3provides an alignment of the RNase III domains of the mouse, human, Drosophila and C. elegans RNase III orthologues.
Two chromosomal locations in both species harbor two neighboring TMC genes, Tmc5 and Tmc7 on murine chromosome 7, and Tmc6 and Tmc8 on murine chromosome 11; the human orthologues are located on the syntenic regions of chromosomes 16 and 17, respectively [ 7 ] . An additional murine locus on chromosome 8 represents a partial gene fragment, likely a pseudogene of Tmc2 .
The position of the first intron in DmLozenge is conserved in one of the mosquito genes ( AgLozenge ), indicating that these two genes are orthologues, which is confirmed by a phylogenetic analysis of sequences (see below).
Two mammalian RNase III orthologues have been identified, and exhibit common domains as well as apparently unique features.
The absence of identifiable orthologues of Tnfrh1 and Tnfrh2 in the human genome suggests that both of these genes arose subsequent to the divergence of placental mammals.
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