Example sentences for: ortholog

How can you use “ortholog” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, RP L18, which was significantly down-regulated by NGF, has been reported to negatively regulate double-stranded RNA (dsRNA)-activated protein kinase (PKR) [ 45 ] . As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] . As one last example, rat RP L9 which we found to be up-regulated by NGF starting within a few hours and maximally by 8 hrs, has been shown to be the ortholog of the yeast gene grc5 which appears to be involved in multiple cellular functions including growth control, cytoskeleton control and energy metabolism [ 47 ] . Identification of NGF-regulated RPs should now facilitate exploration of their potential roles in the responses of cells to neurotrophins.

  • The ortholog of the vertebrate LRAT, Egl-29 in C. elegans has been implicated in the development of the vulva [ 57].

  • This might be especially pertinent if the host downregulates the endogenous ortholog in response to the infection.

  • Rad52 functions in conjunction with the RecA ortholog, the RAD51 recombinase in double-strand break repair and meiotic recombination [ 6 ] . RAD52 binds ssDNA during recombination and also shows a quaternary organization similar to those of RecT/Redβ and ERF [ 16 26 ] . However, RAD52-like proteins showed no detectable sequence similarity with either the ERF or the RecT/Redβ-like proteins.

  • 3 and its Drosophila ortholog.


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