Words similar to ortholog
Example sentences for: ortholog
How can you use “ortholog” in a sentence? Here are some example sentences to help you improve your vocabulary:
The single archaeal fusion, the Arachaeoglobus fulgidus protein AF0227, belongs to one of these clusters and shows a strongly supported affinity with the ortholog from the hyperthermophilic bacterium Thermotoga maritima . (Figure 4a,4b).
To confirm these data and gain some hints for the existence of a CCR4-NOT complex in mammals, we investigated whether the interaction between yCCR4 and yPOP2 in the CCR4-NOT complex is conserved for the human ortholog, hCCR4.
1) to its ancestral ortholog, it may suit the genomics and/or evolutionary community to devise new terminology for such cases.
For example, a slimb allele shows defects in centrosome duplication control [ 34 ] , and slimb null cells undergo apoptosis [ 35 ] . Both effects could be explained by a failure to inactivate E2F, as E2F promotes centrosome duplication in mammalian cells [ 36 ] and E2F can induce apoptosis [ 12 ] [ 13 ] . A link between Slimb function and the RB/E2F pathway of cell proliferation control is also suggested by the genetic interaction between the C. elegans slimb ortholog lin-23 and the RBF ortholog lin-35 in which lin-35 function limits the severity of the loss of lin-23 [ 37 ] . Since RBF is an important modifier of E2F activity, perhaps this interaction is a reflection of the action of both Lin-23 and Lin-35 on E2F.
Hsp90 is a highly conserved molecular chaperone necessary for viability and for proper folding, processing, and function of proteins involved in several signal transduction pathways [ 31 32 ] . Interestingly, mammalian hsp90 has been shown to specifically interact with PP5, and this interaction may have important consequences in PP5 structure and function [ 33 34 ] . An hsp90 ortholog has been described in Pf [ 35 ] , but its function is currently unknown.
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