Example sentences for: orthology

How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Only two of the 560 protein-coding genes that show clear orthology between E. coli and Buchnera would have been removed (due to absence from both Vibrio cholerae and Yersinia pestis ). The two genes ( dnaC and dnaT ) are linked in both Buchnera and E. coli and were retained in the ancestor.

  • If the top orthology bootstrap value is low, then the query sequence is likely to have no ortholog in the Pfam alignment.

  • orthologs nonetheless exhibit marginal orthology bootstrap values (in the range of 70% or even lower).

  • In light of the similarities of certain genes generated by CoreGenes, one may ponder their relationships upon further and closer inspection, given that the high BLAST scores between two genes do not always imply an orthologous relationship [ 30 ] . In other words, the complexity of these BLAST scores suggests that the user should perform rigorous phylogenetic analysis of each set of homologous genes to determine true orthology.

  • Output: A list (as in Figure 7) of proteins orthologous to Q , sorted according to a bootstrap confidence value (based on orthology, super-orthology, or subtree-neighborings).

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