Example sentences for: orthology

How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Output: A list (as in Figure 7) of proteins orthologous to Q , sorted according to a bootstrap confidence value (based on orthology, super-orthology, or subtree-neighborings).

  • Inconsistency between orthology bootstrap values and sequence similarity

  • For a given gene pair AB (A and B are separate genes and are encoded continuously on the chromosome) in the target genome, the presence of AB in a reference genome is recorded when we detect the presence of either an A'B' or a B'A' gene cluster, where gene A' is a homolog of gene A and gene B' is a homolog of gene B. There are many established methods for detecting homology or orthology, for example, membership in the same COG (Clusters of Orthologous Genes) [ 12].

  • Similarly to the issues described in the previous section, the detection of such examples is complicated by the fact that for many cases in which a discrepancy between orthology bootstrap values and sequence similarity exists, all sequences in the Pfam alignment appear to have to same function, the Pfam family is lineage specific, or the annotations are too poor/confusing to make any kind of inference.

  • Next, we determined the distribution of the top orthology bootstrap values.


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