Words similar to orthology
Example sentences for: orthology
How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:
Storm, Sonnhammer, and colleagues have recently developed similar ideas and procedures in a program called ORTHOSTRAPPER [ 44 45 ] . One distinction between the two approaches is that ORTHOSTRAPPER's orthology determination procedure does not employ a species tree for duplication inference; it uses a heuristic based on sequence similarity rather than a formally correct phylogenetic means of inferring orthology.
We were next interested in the number of sequences in the two proteomes for which the orthology bootstrap values do not correspond to sequence similarity (Table 5).
Similarly to the issues described in the previous section, the detection of such examples is complicated by the fact that for many cases in which a discrepancy between orthology bootstrap values and sequence similarity exists, all sequences in the Pfam alignment appear to have to same function, the Pfam family is lineage specific, or the annotations are too poor/confusing to make any kind of inference.
In many cases a discrepancy between orthology bootstrap values and sequence similarity is caused by orthologs in only phylogenetically distant (relatively to the query sequence) species.
Determination of phylogenetic distribution was based on the 'Pip-maker' analyses [ 56] for viewing orthology among enteric and related bacteria as produced by McClelland et al.
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