Example sentences for: orthology

How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The information on orthologous genes in prokaryotic genomes and the yeast genome was derived from the COGs as in the previous approach, and the orthology data were similarly represented as a 0/1 matrix of presence-absence of the analyzed genomes in the COGs.

  • However, the Pyrococcus analysis yielded five cases where orthology could not be ascertained.

  • Similarly to the issues described in the previous section, the detection of such examples is complicated by the fact that for many cases in which a discrepancy between orthology bootstrap values and sequence similarity exists, all sequences in the Pfam alignment appear to have to same function, the Pfam family is lineage specific, or the annotations are too poor/confusing to make any kind of inference.

  • Storm, Sonnhammer, and colleagues have recently developed similar ideas and procedures in a program called ORTHOSTRAPPER [ 44 45 ] . One distinction between the two approaches is that ORTHOSTRAPPER's orthology determination procedure does not employ a species tree for duplication inference; it uses a heuristic based on sequence similarity rather than a formally correct phylogenetic means of inferring orthology.

  • Only two of the 560 protein-coding genes that show clear orthology between E. coli and Buchnera would have been removed (due to absence from both Vibrio cholerae and Yersinia pestis ). The two genes ( dnaC and dnaT ) are linked in both Buchnera and E. coli and were retained in the ancestor.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast