Words similar to orthology
Example sentences for: orthology
How can you use “orthology” in a sentence? Here are some example sentences to help you improve your vocabulary:
Of the 204 proteins that could be calibrated for time estimation, the orthology of roughly half (116 proteins) was ambiguous for unknown reasons (e.g.
An indication of this problem (besides a discrepancy between orthology bootstrap values and sequence similarity) is the meeting of the following three conditions: A query sequence has (i) likely orthologs and (ii) likely subtree-neighbors in other species than the query itself, yet (iii) there is no significant overlap between the orthologs and the subtree-neighbors.
orthologs nonetheless exhibit marginal orthology bootstrap values (in the range of 70% or even lower).
For a given gene pair AB (A and B are separate genes and are encoded continuously on the chromosome) in the target genome, the presence of AB in a reference genome is recorded when we detect the presence of either an A'B' or a B'A' gene cluster, where gene A' is a homolog of gene A and gene B' is a homolog of gene B. There are many established methods for detecting homology or orthology, for example, membership in the same COG (Clusters of Orthologous Genes) [ 12].
In light of the similarities of certain genes generated by CoreGenes, one may ponder their relationships upon further and closer inspection, given that the high BLAST scores between two genes do not always imply an orthologous relationship [ 30 ] . In other words, the complexity of these BLAST scores suggests that the user should perform rigorous phylogenetic analysis of each set of homologous genes to determine true orthology.
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